(Q47927511)

6 February 2018

title

Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells (English)

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6 February 2018

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X-X Li

1

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6 February 2018

H-S Zhang

2

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6 February 2018

Y-M Xu

3

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6 February 2018

R-J Zhang

4

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6 February 2018

Y Chen

5

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6 February 2018

L Fan

6

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6 February 2018

Y-Q Qin

7

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6 February 2018

Y Liu

8

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6 February 2018

M Li

9

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6 February 2018

J Fang

10

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6 February 2018

language of work or name

English

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publication date

21 August 2017

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6 February 2018

published in

Oncogene

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6 February 2018

volume

36

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6 February 2018

issue

48

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6 February 2018

page(s)

6738-6746

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6 February 2018

https://scigraph.springernature.com/pub.10.1038/onc.2017.284

exact match

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cites work

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The endoplasmic reticulum stress response in immunity and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress-induced cell death mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The impact of the endoplasmic reticulum protein-folding environment on cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The role of endoplasmic reticulum stress in human pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The role of the unfolded protein response in tumour development: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Endoplasmic reticulum stress in malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The von Hippel-Lindau protein pVHL inhibits ribosome biogenesis and protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Wnt signaling in stem and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

WNT signalling pathways as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

PERK mediates cell-cycle exit during the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Wnt signalling and its impact on development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress induces epithelial differentiation in the mouse oesophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

PAX2 protein induces expression of cyclin D1 through activating AP-1 protein and promotes proliferation of colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

Primary mouse small intestinal epithelial cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.284

The unfolded protein response as a target for cancer therapy

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28825721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2017.284

1 reference

6 February 2018

1 reference

6 February 2018