(Q47971862)

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Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation

scientific article published on 7 February 2017

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Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation (English)

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Miriam A. Shelef

object named as

Miriam A Shelef

10

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Claus H. Nielsen

7

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Claus H Nielsen

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

author name string

Mandar Bawadekar

1

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Daeun Shim

2

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Chad J Johnson

3

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Thomas F Warner

4

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Ryan Rebernick

5

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Dres Damgaard

6

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Ger J M Pruijn

8

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Jeniel E Nett

9

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Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

publication date

7 February 2017

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Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

Journal of Autoimmunity

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Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

80

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

39-47

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5422119/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The Extracellular Matrix of Candida albicans Biofilms Impairs Formation of Neutrophil Extracellular Traps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Chemical Proteomic Platform To Identify Citrullinated Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Peptidylarginine deiminase type 4 deficiency reduced arthritis severity in a glucose-6-phosphate isomerase-induced arthritis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

PADI2 is significantly associated with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Local administration of glucocorticoids decreases synovial citrullination in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Anti-CCP antibodies: the past, the present and the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Optimizing a Candida biofilm microtiter plate model for measurement of antifungal susceptibility by tetrazolium salt assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Citrullination is an inflammation-dependent process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Regulation of plasma-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

22 June 2018

High-Titer Rheumatoid Arthritis Antibodies Preferentially Bind Fibrinogen Citrullinated by Peptidylarginine Deiminase 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Increased levels of peptidylarginine deiminase 2 in synovial fluid from anti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

The human peptidylarginine deiminases type 2 and type 4 have distinct substrate specificities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Generation of monoclonal antibodies against peptidylarginine deiminase 2 (PAD2) and development of a PAD2-specific enzyme-linked immunosorbent assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Peptidylarginine deiminase expression and activity in PAD2 knock-out and PAD4-low mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

PADI4 polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Preparation of a monoclonal antibody to citrullinated epitopes: its characterization and some applications to immunohistochemistry in human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Purification and characterization of peptidylarginine deiminase from rabbit skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5422119

14 August 2018

Association of single nucleotide polymorphisms (SNPs) of PADI4 gene with rheumatoid arthritis (RA) in Indian population

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/28188029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JAUT.2017.01.006

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 June 2018

http://europepmc.org/abstract/PMC/5422119

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