(Q48034381)

7 February 2018

title

PI3Kγ is required for NMDA receptor-dependent long-term depression and behavioral flexibility (English)

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7 February 2018

23

Bong-Kiun Kaang

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7 February 2018

author name string

Jae-Ick Kim

1

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7 February 2018

Hye-Ryeon Lee

2

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7 February 2018

Su-eon Sim

3

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7 February 2018

Jinhee Baek

4

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7 February 2018

Nam-Kyung Yu

5

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7 February 2018

Jun-Hyeok Choi

6

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7 February 2018

Hyoung-Gon Ko

7

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7 February 2018

Yong-Seok Lee

8

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7 February 2018

Soo-Won Park

9

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7 February 2018

Chuljung Kwak

10

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7 February 2018

Sung-Ji Ahn

11

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7 February 2018

So Yoen Choi

12

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7 February 2018

Hyun Kim

13

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7 February 2018

Kyoung-Han Kim

14

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7 February 2018

Peter H Backx

15

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7 February 2018

Clarrisa A Bradley

16

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7 February 2018

Eunjoon Kim

17

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7 February 2018

Deok-Jin Jang

18

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7 February 2018

Kyungmin Lee

19

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7 February 2018

Sang Jeong Kim

20

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7 February 2018

Min Zhuo

21

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7 February 2018

Graham L Collingridge

22

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7 February 2018

language of work or name

English

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publication date

23 October 2011

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7 February 2018

published in

Nature Neuroscience

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7 February 2018

volume

14

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7 February 2018

issue

11

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7 February 2018

page(s)

1447-1454

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7 February 2018

Signalling through the lipid products of phosphoinositide-3-OH kinase

cites work

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21 January 2018

Phosphoinositide kinases

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The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

21 January 2018

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Structure and function of phosphoinositide 3-kinases.

21 January 2018

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Signalling through Class I PI3Ks in mammalian cells

21 January 2018

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PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

21 January 2018

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Phosphoinositide 3-kinase gamma regulates cardiac contractility by locally controlling cyclic adenosine monophosphate levels

21 January 2018

1 reference

Important roles of PI3Kgamma in osteoclastogenesis and bone homeostasis

21 January 2018

1 reference

PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis

21 January 2018

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Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat.

21 January 2018

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Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocampal interneurons.

21 January 2018

1 reference

A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala

21 January 2018

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Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

21 January 2018

1 reference

Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression.

21 January 2018

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Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner

21 January 2018

1 reference

Orexins/hypocretins control bistability of hippocampal long-term synaptic plasticity through co-activation of multiple kinases.

21 January 2018

1 reference

PI3 kinase signaling is required for retrieval and extinction of contextual memory

21 January 2018

1 reference

Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation

21 January 2018

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LY294002, an inhibitor of phosphoinositide 3-kinase given into rat hippocampus impairs acquisition, consolidation and retrieval of memory for one-trial step-down inhibitory avoidance

21 January 2018

1 reference

Differential mRNA expression and subcellular locations of PI3-kinase isoforms in sympathetic and sensory neurons

21 January 2018

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity

21 January 2018

1 reference

Plasticity of NMDA receptor NR2B subunit in memory and chronic pain

21 January 2018

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

21 January 2018

1 reference

Beyond parallel fiber LTD: the diversity of synaptic and non-synaptic plasticity in the cerebellum

21 January 2018

1 reference

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

21 January 2018

1 reference

A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases

21 January 2018

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors

21 January 2018

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Long-term depression in the CNS.

21 January 2018

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Ras and Rap control AMPA receptor trafficking during synaptic plasticity

21 January 2018

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Rap2-JNK removes synaptic AMPA receptors during depotentiation

21 January 2018

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Rap1 signalling: adhering to new models

21 January 2018

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Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility

21 January 2018

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The emerging mechanisms of isoform-specific PI3K signalling

21 January 2018

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Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

21 January 2018

1 reference

A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context

21 January 2018

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Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition

21 January 2018

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Novelty acquisition is associated with induction of hippocampal long-term depression.

21 January 2018

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Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment.

21 January 2018

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Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory

21 January 2018

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Long-term depression of mGluR1 signaling

21 January 2018

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Phosphorylation-dependent interaction of the N-methyl- d-aspartate receptor epsilon2 subunit with phosphatidylinositol 3-kinase

21 January 2018

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Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region

21 January 2018

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12 December 2020

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

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12 December 2020

Differential regulation of lipid and protein kinase activities of phosphoinositide 3-kinase gamma in vitro

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12 December 2020

Tissue distribution and subcellular localization of a G-protein activated phosphoinositide 3-kinase. An immunohistochemical study.

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12 December 2020

Phosphatidylinositol 3-kinases regulate ERK and p38 MAP kinases in canine colonic smooth muscle

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12 December 2020

N-ethylmaleimide blocks depolarization-induced suppression of inhibition and enhances GABA release in the rat hippocampal slice in vitro

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12 December 2020

Long-term potentiation in dentate gyrus of the rat is inhibited by the phosphoinositide 3–kinase inhibitor, wortmannin

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12 December 2020

Phosphatidylinositol 3-Kinase Regulates the Induction of Long-Term Potentiation through Extracellular Signal-Related Kinase-Independent Mechanisms

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12 December 2020

Identifiers

DOI

10.1038/NN.2937

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7 February 2018

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7 February 2018