(Q48097831)

8 February 2018

title

The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2. (English)

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8 February 2018

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Timothy A Bolger

1

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8 February 2018

Xuan Zhao

2

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8 February 2018

Todd J Cohen

3

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8 February 2018

Chih-Cheng Tsai

4

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8 February 2018

Tso-Pang Yao

5

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8 February 2018

language of work or name

English

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publication date

23 July 2007

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8 February 2018

Journal of Biological Chemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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8 February 2018

volume

282

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8 February 2018

issue

40

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8 February 2018

page(s)

29186-29192

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8 February 2018

SCA1 molecular genetics: a history of a 13 year collaboration against glutamines

cites work

1 reference

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A century-old debate on protein aggregation and neurodegeneration enters the clinic

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Identification and characterization of the gene causing type 1 spinocerebellar ataxia.

21 January 2018

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Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors

21 January 2018

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Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.

21 January 2018

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Polyglutamine is not all: the functional role of the AXH domain in the ataxin-1 protein

21 January 2018

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ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology

21 January 2018

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Identification of genes that modify ataxin-1-induced neurodegeneration.

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Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice

21 January 2018

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Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.

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Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death.

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The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking.

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Neuronal activity-dependent cell survival mediated by transcription factor MEF2

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Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis

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Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

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Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications

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HDAC4 deacetylase associates with and represses the MEF2 transcription factor

21 January 2018

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Polyglutamine neurodegeneration: minding your Ps and Qs.

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Hosting neurotoxicity in polyglutamine disease.

21 January 2018

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

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CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

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A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.

21 January 2018

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Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

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Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

21 January 2018

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SUMOylation substrates in neuronal intranuclear inclusion disease

21 January 2018

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

1 reference

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M704182200

1 reference

8 February 2018

PubMed ID

17646162

1 reference

8 February 2018