(Q48108091)

8 February 2018

title

Distribution and function of voltage-gated sodium channels in the nervous system. (English)

1 reference

8 February 2018

author name string

Jun Wang

series ordinal

1

1 reference

8 February 2018

Shao-Wu Ou

series ordinal

2

1 reference

8 February 2018

Yun-Jie Wang

series ordinal

3

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8 February 2018

publication date

18 September 2017

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8 February 2018

published in

Channels

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8 February 2018

volume

11

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8 February 2018

page(s)

534-554

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8 February 2018

issue

6

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8 February 2018

Voltage-gated sodium channel organization in neurons: protein interactions and trafficking pathways.

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Alternative splicing modulates inactivation of type 1 voltage-gated sodium channels by toggling an amino acid in the first S3-S4 linker

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Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5

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Analysis of four novel variants of Nav1.5/SCN5A cloned from the brain

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Alternative splicing of Nav1.5: an electrophysiological comparison of 'neonatal' and 'adult' isoforms and critical involvement of a lysine residue.

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Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion

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Expression and distribution of voltage-gated sodium channels in the cerebellum

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Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels

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Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

21 January 2018

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Existence of distinct sodium channel messenger RNAs in rat brain

21 January 2018

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A rat brain Na+ channel alpha subunit with novel gating properties

21 January 2018

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Primary structure, chromosomal localization, and functional expression of a voltage-gated sodium channel from human brain

21 January 2018

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Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

21 January 2018

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Induction of sodium channel clustering by oligodendrocytes

21 January 2018

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Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier

21 January 2018

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An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier

21 January 2018

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Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp

21 January 2018

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Expression of sodium channels Nav1.2 and Nav1.6 during postnatal development of the retina.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments.

21 January 2018

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Distinct contributions of Na(v)1.6 and Na(v)1.2 in action potential initiation and backpropagation.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Molecular identity of dendritic voltage-gated sodium channels

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Biology of cardiac sodium channel Nav1.5 expression

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The cardiac sodium channel mRNA is expressed in the developing and adult rat and human brain.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

NaV1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Cloning and expression of the two new variants of Nav1.5/SCN5A in rat brain

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Multiple Nav1.5 isoforms are functionally expressed in the brain and present distinct expression patterns compared with cardiac Nav1.5.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons

21 January 2018

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Sodium channel beta subunits: anything but auxiliary

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Crystallographic insights into sodium-channel modulation by the β4 subunit

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Crystal Structure and Molecular Imaging of the Nav Channel 3 Subunit Indicates a Trimeric Assembly

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Structure of the Nav1.4-β1 Complex from Electric Eel.

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channel β subunits: emerging targets in channelopathies

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Na+ channel Scn1b gene regulates dorsal root ganglion nociceptor excitability in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Molecular cloning and functional expression of the human sodium channel β1B subunit, a novel splicing variant of the β1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Expression of the sodium channel beta3 subunit in injured human sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Molecular properties of voltage-sensitive sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Na+ channel-dependent recruitment of Navβ4 to axon initial segments and nodes of Ranvier

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channels in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Future directions for epilepsy research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channel mutations in epilepsy and other neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Inherited disorders of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Human epilepsies: interaction of genetic and acquired factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Channel, neuronal and clinical function in sodium channelopathies: from genotype to phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Persistent Sodium Current and Its Role in Epilepsy

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

NaV1.1 channels and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channel SCN1A and epilepsy: mutations and mechanisms

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium and potassium channel dysfunctions in rare and common idiopathic epilepsy syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Inherited neuronal ion channelopathies: new windows on complex neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

21 January 2018

Dravet syndrome history

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Model systems for studying cellular mechanisms of SCN1A-related epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

New SCN5A mutation in a SUDEP victim with idiopathic epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Coexistence of epilepsy and Brugada syndrome in a family with SCN5A mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

A functional null mutation of SCN1B in a patient with Dravet syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channels: therapeutic targets for pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channelopathies and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channels: mutations, channelopathies and targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channels and mechanisms of neuropathic pain

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Erythermalgia: molecular basis for an inherited pain syndrome

21 January 2018

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https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

An SCN9A channelopathy causes congenital inability to experience pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The roles of sodium channels in nociception: Implications for mechanisms of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

A stop codon mutation in SCN9A causes lack of pain sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Expression of auxiliary β subunits of sodium channels in primary afferent neurons and the effect of nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Targeting glioma stem cells: a novel framework for brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Molecular characterization of voltage-gated sodium channels in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Enhancement of sodium current in NG108-15 cells during neural differentiation is mainly due to an increase in NaV1.7 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-sensitive ion channels and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Expression of neonatal Nav1.5 in human brain astrocytoma and its effect on proliferation, invasion and apoptosis of astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium ion channel mutations in glioblastoma patients correlate with shorter survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The effects of antiepileptic drugs on the growth of glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The up-regulation of voltage-gated sodium channel Nav1.6 expression following fluid percussion traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Differential pattern of expression of voltage-gated sodium channel genes following ischemic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channel function and expression in injured and uninjured rat dorsal root ganglia neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Down-regulation of the sodium channel Na(v)1.1 alpha-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Changes in expression of voltage-dependent ion channel subunits in dorsal root ganglia of rats with radicular injury and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Mechanisms of disease: sodium channels and neuroprotection in multiple sclerosis-current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Sodium channels contribute to microglia/macrophage activation and function in EAE and MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Phenytoin protects central axons in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Axonal protection using flecainide in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

New variants of Nav1.5/SCN5A encode Na+ channels in the brain

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Upregulation of Sodium Channel Nav1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Cloning, distribution and functional analysis of the type III sodium channel from human brain

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Developmental and regional expression of sodium channel isoform NaCh6 in the rat central nervous system.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

Type I and type II Na(+) channel alpha-subunit polypeptides exhibit distinct spatial and temporal patterning, and association with auxiliary subunits in rat brain.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5786190

China must provide education on HIV

2 November 2018

1 reference

https://api.crossref.org/works/10.1080%2F19336950.2017.1380758

Voltage-gated sodium channel Nav1.1, Nav1.3 and beta1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat

21 January 2018

1 reference

12 December 2020

Mechanism of ion permeation and selectivity in a voltage gated sodium channel

1 reference

12 December 2020

Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons

1 reference

12 December 2020

Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states

1 reference

12 December 2020

Axonal protection achieved in a model of multiple sclerosis using lamotrigine

1 reference

12 December 2020

Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine

1 reference

12 December 2020

Spectrum of SCN1A gene mutations associated with Dravet syndrome: analysis of 333 patients

1 reference

12 December 2020

The Molecular Basis of Neuronal Excitability

1 reference

12 December 2020

Sodium channels and pain

1 reference

12 December 2020

Effects of a Chronic Compression of the Dorsal Root Ganglion on Voltage-Gated Na+ and K+ Currents in Cutaneous Afferent Neurons

1 reference

12 December 2020

Distribution of voltage-gated sodium channel alpha-subunit and beta-subunit mRNAs in human hippocampal formation, cortex, and cerebellum

1 reference

12 December 2020

10.1080/19336950.2017.1380758

Identifiers

DOI

1 reference

8 February 2018

0 references

1 reference

8 February 2018