(Q48117214)

English

Sulforaphane Ameliorates 3-Nitropropionic Acid-Induced Striatal Toxicity by Activating the Keap1-Nrf2-ARE Pathway and Inhibiting the MAPKs and NF-κB Pathways.

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scholarly article

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

Sulforaphane Ameliorates 3-Nitropropionic Acid-Induced Striatal Toxicity by Activating the Keap1-Nrf2-ARE Pathway and Inhibiting the MAPKs and NF-κB Pathways. (English)

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

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1 reference

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author name string

Minhee Jang

1

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

Ik-Hyun Cho

2

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

publication date

23 June 2015

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

Molecular Neurobiology

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

53

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

4

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

2619-2635

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

https://scigraph.springernature.com/pub.10.1007/s12035-015-9230-2

0 references

Mitochondria in Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

The role of oxidative stress in Huntington's disease: are antioxidants good therapeutic candidates?

1 reference

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21 January 2018

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

1 reference

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21 January 2018

Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington's disease patients

1 reference

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21 January 2018

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.

1 reference

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21 January 2018

Chronic microglial activation and progressive dopaminergic neurotoxicity.

1 reference

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21 January 2018

Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation

1 reference

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21 January 2018

3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: past, present and future.

1 reference

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21 January 2018

Pretreatment with Bacopa monnieri extract offsets 3-nitropropionic acid induced mitochondrial oxidative stress and dysfunctions in the striatum of prepubertal mouse brain

1 reference

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21 January 2018

Toward clinical application of the Keap1-Nrf2 pathway

1 reference

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21 January 2018

The Keap1-Nrf2 cell defense pathway--a promising therapeutic target?

1 reference

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21 January 2018

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases

1 reference

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21 January 2018

Sulforaphane: translational research from laboratory bench to clinic

1 reference

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21 January 2018

Molecular basis for chemoprevention by sulforaphane: a comprehensive review.

1 reference

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21 January 2018

Activation of the nuclear factor E2-related factor 2/antioxidant response element pathway is neuroprotective after spinal cord injury

1 reference

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21 January 2018

Sulforaphane as a potential protective phytochemical against neurodegenerative diseases

1 reference

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21 January 2018

Neuroprotective effects of sulforaphane after contusive spinal cord injury.

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21 January 2018

A call for transparent reporting to optimize the predictive value of preclinical research

1 reference

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21 January 2018

Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses.

1 reference

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21 January 2018

Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death

1 reference

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21 January 2018

Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death.

1 reference

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21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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21 January 2018

The 3-NP Model of Striatal Neurodegeneration

1 reference

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21 January 2018

Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid

1 reference

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21 January 2018

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

1 reference

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21 January 2018

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

The transcription factor Nrf2 is a therapeutic target against brain inflammation

1 reference

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21 January 2018

NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Sulforaphane suppresses LPS-induced inflammation in primary rat microglia

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

tBHQ inhibits LPS-induced microglial activation via Nrf2-mediated suppression of p38 phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes

1 reference

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21 January 2018

Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase

1 reference

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21 January 2018

Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells.

1 reference

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21 January 2018

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

1 reference

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21 January 2018

Do glial cells play an anti-oxidative role in Huntington's disease?

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease

1 reference

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21 January 2018

Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease

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21 January 2018

Targets for future clinical trials in Huntington's disease: what's in the pipeline?

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21 January 2018

MAPKs: new targets for neurodegeneration

1 reference

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21 January 2018

Activation of mitogen-activated protein kinases in gerbil hippocampus with ischemic tolerance induced by 3-nitropropionic acid.

1 reference

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21 January 2018

Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

1 reference

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21 January 2018

Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2.

1 reference

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21 January 2018

Age-associated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid

1 reference

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21 January 2018

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

1 reference

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21 January 2018

Deranged neuronal calcium signaling and Huntington disease.

1 reference

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21 January 2018

Role of NF-kappaB and MAPKs in light-induced photoreceptor apoptosis

1 reference

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21 January 2018

Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9230-2

21 January 2018

Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone

1 reference

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21 January 2018

Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26096705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Korean Red Ginseng Extract Attenuates 3-Nitropropionic Acid-Induced Huntington's-Like Symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/26096705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26096705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethyl pyruvate ameliorates 3-nitropropionic acid-induced striatal toxicity through anti-neuronal cell death and anti-inflammatory mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/26096705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-015-9230-2

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

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1 reference

https://api.fatcat.wiki/v0/release/dehvmtt6vfhljhj37uwx2t6vx4

24 November 2022

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1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/26096705

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