(Q48128009)

http://europepmc.org/abstract/PMC/5785926

6 July 2018

title

An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome (English)

1 reference

http://europepmc.org/abstract/PMC/5785926

6 July 2018

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jishu Xu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Philip L. De Jager

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

2

Charles C White

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

10

David A Bennett

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Bernard Ng

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hans-Ulrich Klein

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Solveig K Sieberts

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Cristin McCabe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Lei Yu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Chris Gaiteri

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Sara Mostafavi

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

4 September 2017

1 reference

http://europepmc.org/abstract/PMC/5785926

6 July 2018

published in

Nature Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

1418-1426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

Gene expression elucidates functional impact of polygenic risk for schizophrenia

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

A spectral approach integrating functional genomic annotations for coding and noncoding variants

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Partitioning heritability by functional annotation using genome-wide association summary statistics

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

A gene-based association method for mapping traits using reference transcriptome data

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Cell Specific eQTL Analysis without Sorting Cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Second-generation PLINK: rising to the challenge of larger and richer datasets

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

The contribution of de novo coding mutations to autism spectrum disorder

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Genetic variability in the regulation of gene expression in ten regions of the human brain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Biological insights from 108 schizophrenia-associated genetic loci

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Inflammasomes in the CNS.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Identification of genetic variants that affect histone modifications in human cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Transcriptome and genome sequencing uncovers functional variation in humans

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

The Genotype-Tissue Expression (GTEx) project

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

An integrated map of genetic variation from 1,092 human genomes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Overview and findings from the rush Memory and Aging Project

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Overview and findings from the religious orders study

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

ChromHMM: automating chromatin-state discovery and characterization

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Dissecting the regulatory architecture of gene expression QTLs

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

A genome-wide scan for common variants affecting the rate of age-related cognitive decline

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Annotating non-coding regions of the genome

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Understanding mechanisms underlying human gene expression variation with RNA sequencing

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Disentangling molecular relationships with a causal inference test

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Common genetic variation and human traits

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

The RNA binding protein CPEB regulates dendrite morphogenesis and neuronal circuit assembly in vivo

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Statistical significance for genomewide studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Further evidence for the association between the LSM1 gene and schizophrenia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

NALP1/NLRP1 genetic variants are associated with Alzheimer disease

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5785926

Human-specific histone methylation signatures at transcription start sites in prefrontal neurons

14 August 2018

1 reference

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 January 2018

1 reference

Principal components analysis corrects for stratification in genome-wide association studies

21 January 2018

1 reference

Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease

21 January 2018

1 reference

Comprehensive comparative analysis of strand-specific RNA sequencing methods

21 January 2018

1 reference

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

21 January 2018

1 reference

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

21 January 2018

1 reference

Adjusting batch effects in microarray expression data using empirical Bayes methods

21 January 2018

1 reference

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

21 January 2018

1 reference

Supervised normalization of microarrays

21 January 2018

1 reference

Fast and accurate short read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

Model-based analysis of ChIP-Seq (MACS)

21 January 2018

1 reference

Design and analysis of ChIP-seq experiments for DNA-binding proteins

21 January 2018

1 reference

Normalizing RNA-sequencing data by modeling hidden covariates with prior knowledge

21 January 2018

1 reference

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels

21 January 2018

1 reference

Histone Acetylome-wide Association Study of Autism Spectrum Disorder.

21 January 2018

1 reference

The UCSC Genome Browser database: 2015 update

21 January 2018

1 reference

Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder

21 January 2018

1 reference

Meta-analysis of genome-wide association studies of anxiety disorders.

21 January 2018

1 reference

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

21 January 2018

1 reference

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

21 January 2018

1 reference

Sparse whole-genome sequencing identifies two loci for major depressive disorder

21 January 2018

1 reference

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

21 January 2018

1 reference

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

21 January 2018

1 reference

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

21 January 2018

1 reference

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

21 January 2018

1 reference

Improving power in genome-wide association studies: weights tip the scale

21 January 2018

1 reference

Histone H3 acetylated at lysine 9 in promoter is associated with low nucleosome density in the vicinity of transcription start site in human cell

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NN.4632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28869584%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

28869584

1 reference