(Q48152553)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29377001%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity (English)

1 reference

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13 March 2020

0 references

12

1 reference

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13 March 2020

Robert S. Langer, Jr.

13

object named as

Robert Langer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29377001%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Victor E. Koteliansky

11

object named as

Victor Koteliansky

1 reference

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13 March 2020

9

Lihua Julie Zhu

1 reference

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13 March 2020

14

Daniel G Anderson

1 reference

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13 March 2020

3

Sneha Suresh

1 reference

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13 March 2020

8

Roman L Bogorad

1 reference

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13 March 2020

10

Scot A Wolfe

1 reference

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13 March 2020

7

Junmei Ding

1 reference

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13 March 2020

4

Suet-Yan Kwan

1 reference

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13 March 2020

author name string

Hao Yin

1

1 reference

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13 March 2020

Chun-Qing Song

2

1 reference

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13 March 2020

Qiongqiong Wu

5

1 reference

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13 March 2020

Stephen Walsh

6

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13 March 2020

publication date

29 January 2018

1 reference

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13 March 2020

published in

Nature Chemical Biology

1 reference

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13 March 2020

volume

14

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13 March 2020

issue

3

1 reference

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13 March 2020

page(s)

311-316

1 reference

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https://scigraph.springernature.com/pub.10.1038/nchembio.2559

13 March 2020

exact match

0 references

cites work

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1 reference

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Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering

14 June 2018

1 reference

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Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

14 June 2018

1 reference

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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Rationally engineered Cas9 nucleases with improved specificity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Synthetic CRISPR RNA-Cas9-guided genome editing in human cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

DNA-binding-domain fusions enhance the targeting range and precision of Cas9.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Cas9 gRNA engineering for genome editing, activation and repression.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

In vivo genome editing using Staphylococcus aureus Cas9

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Therapeutic genome editing: prospects and challenges

14 June 2018

1 reference

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Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Easy quantitative assessment of genome editing by sequence trace decomposition

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Improved vectors and genome-wide libraries for CRISPR screening

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

DNA-guided DNA interference by a prokaryotic Argonaute

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

DNA targeting specificity of RNA-guided Cas9 nucleases

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

RNA-guided human genome engineering via Cas9

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Multiplex genome engineering using CRISPR/Cas systems

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Designing chemically modified oligonucleotides for targeted gene silencing

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

An unbiased genome-wide analysis of zinc-finger nuclease specificity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

The orientation and dynamics of the C2'-OH and hydration of RNA and DNA.RNA hybrids

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Conjugation and Evaluation of Triazole-Linked Single Guide RNA for CRISPR-Cas9 Gene Editing

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

Relative thermodynamic stability of DNA, RNA, and DNA:RNA hybrid duplexes: relationship with base composition and structure.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902734

14 August 2018

Identifiers

DOI

10.1038/NCHEMBIO.2559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29377001%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29377001%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference