(Q48197704)

http://europepmc.org/abstract/PMC/5481563

15 July 2018

title

Thrombin activation of protein C requires prior processing by a liver proprotein convertase (English)

1 reference

http://europepmc.org/abstract/PMC/5481563

15 July 2018

author

Nabil Seidah

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Johann Guillemot

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Annik Prat

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Rachid Essalmani

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Delia Susan-Resiga

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Woojin Kim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Vatsal Sachan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Zuhier Awan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ann Chamberland

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Marie-Claude Asselin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Kévin Ly

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Roxane Desjardins

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Robert Day

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

3 May 2017

1 reference

http://europepmc.org/abstract/PMC/5481563

15 July 2018

published in

Journal of Biological Chemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

10564-10573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity.

9 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Loss of endothelial furin leads to cardiac malformation and early postnatal death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The biology and therapeutic targeting of the proprotein convertases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The endothelial cell protein C receptor: its role in thrombosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

In vivo evidence that furin from hepatocytes inactivates PCSK9

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The activation and physiological functions of the proprotein convertases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Activated protein C--an anticoagulant that does more than stop clots

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Furin at the cutting edge: from protein traffic to embryogenesis and disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

SPC4/PACE4 regulates a TGFbeta signaling network during axis formation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Large-scale predictions of secretory proteins from mammalian genomic and EST sequences

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Identification of a region in protein C involved in thrombomodulin-stimulated activation by thrombin: potential repulsion at anion-binding site I in thrombin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The regulation of natural anticoagulant pathways.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: effects of sequence alterations on efficiency of cleavage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Characterization of protein S, a .gamma.-carboxyglutamic acid containing protein from bovine and human plasma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Multifunctional specificity of the protein C/activated protein C Gla domain.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Limited redundancy of the proprotein convertase furin in mouse liver

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Cross-inhibition between furin and lethal factor inhibitors

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Protein C activators from snake venoms and their diagnostic use.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Proteolytic maturation of protein C upon engineering the mouse mammary gland to express furin

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

The occurrence of beta-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481563

Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.770040

Protein C Osaka 10 with aberrant propeptide processing: loss of anticoagulant activity due to an amino acid substitution in the protein C precursor

21 January 2018

1 reference

12 December 2020

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

1 reference

12 December 2020

Endoproteolytic processing of the human protein C precursor by the yeast Kex2 endopeptidase coexpressed in mammalian cells

1 reference

12 December 2020

Five novel mutations located in exons III and IX of the protein C gene in patients presenting with defective protein C anticoagulant activity

1 reference

12 December 2020

Propeptide of human protein C is necessary for .gamma.-carboxylation

1 reference

12 December 2020

Amino acid sequence of the light chain of bovine protein C

1 reference

12 December 2020

Interferences in coagulation tests--evaluation of the 570-nm method on the Dade Behring BCS analyser

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M116.770040

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28468828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

28468828

1 reference