(Q48301354)

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Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/24920625

Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/24920625

0 references

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

Oleh Hornykiewicz

8

object named as

Oleh Hornykiewicz

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

author name string

Alex Rajput

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

Harald Reither

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

José A Obeso

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

Ali H Rajput

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 June 2014

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/24920625

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

34

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

8210-8218

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6608236&resulttype=core&format=json

15 May 2020

Dopamine transporters and neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organochlorine insecticides in substantia nigra in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VMAT-Mediated changes in quantal size and vesicular volume.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The VMAT2 gene in mice and humans: amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repetitive administration of tetrabenazine induces irreversible changes in locomotion and morphology of the substantia nigra in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonian toxin MPTP: action and mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: mechanisms and models

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The brain-stem lesions in Parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The tropical localization and content of noradrenalin and dopamine (3-hydroxytyramine) in the substantia nigra of normal persons and patients with Parkinson's disease.]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa and the progression of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural variants in the vesicular monoamine transporter do not contribute to sporadic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloride ion increases [3H]dopamine accumulation by synaptic vesicles purified from rat striatum: inhibition by thiocyanate ion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of VMAT-2 and DT-diaphorase induce cell death in a substantia nigra-derived cell line--an experimental cell model for dopamine toxicity studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vesicular monoamine transporter-2 activity in alpha-synuclein stably transfected SH-SY5Y cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered vesicular dopamine storage in Parkinson's disease: a premature demise

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective actions of the vesicular monoamine transporter 2 (VMAT2) in monoaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H(+)-ATPase, a primary pump for accumulation of neurotransmitters, is a major constituent of brain synaptic vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association study reveals genetic risk underlying Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of (−) 3H-norepinephrine by storage vesicles prepared from whole rat brain: Properties of the uptake system and its inhibition by drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: a PET, histological and biochemical study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain dopamine-serotonin vesicular transport disease and its treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A marked rise in 5-S-cysteinyl-dopamine levels in guinea-pig striatum following reserpine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromaffin granule proton pump

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine turnover and glutathione oxidation: implications for Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrochemical, pharmacological and electrophysiological evidence of rapid dopamine release and removal in the rat caudate nucleus following electrical stimulation of the median forebrain bundle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine and noradrenaline transport into subcellular vesicles of the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-striatal dialysis coupled to reverse phase high performance liquid chromatography with electrochemical detection: a new method for the study of the in vivo release of endogenous dopamine and metabolites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural degeneration and the transport of neurotransmitters

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical aspects of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24920625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5456-13.2014

1 reference

https://api.fatcat.wiki/v0/release/42dgvkxm7je3lkcs6pfocav5b4

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_42dgvkxm7je3lkcs6pfocav5b4

1 reference

https://api.fatcat.wiki/v0/release/42dgvkxm7je3lkcs6pfocav5b4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/42dgvkxm7je3lkcs6pfocav5b4

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/42dgvkxm7je3lkcs6pfocav5b4

30 July 2022

based on heuristic

mapped directly with Wikidata item

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