(Q48348820)

10 February 2018

title

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice. (English)

1 reference

10 February 2018

1 reference

Ludwig T

1

1 reference

10 February 2018

Fisher P

series ordinal

2

1 reference

10 February 2018

Murty V

series ordinal

3

1 reference

10 February 2018

Efstratiadis A

series ordinal

4

1 reference

10 February 2018

language of work or name

English

0 references

publication date

1 July 2001

1 reference

10 February 2018

published in

Oncogene

1 reference

10 February 2018

volume

20

1 reference

10 February 2018

page(s)

3937-3948

1 reference

10 February 2018

issue

30

1 reference

10 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204512

exact match

0 references

cites work

Functions of the BRCA1 and BRCA2 genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

The BRC repeats are conserved in mammalian BRCA2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Internal repeats in the BRCA2 protein sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

BRCA2 associates with acetyltransferase activity when bound to P/CAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Gene-Expression Profiles in Hereditary Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Transition from squamous cell carcinoma to adenocarcinoma in adenosquamous carcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Transcriptional activation functions in BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Clonal analysis of adenosquamous carcinoma of the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

The mitotic machinery as a source of genetic instability in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Inducible gene targeting in mice using the Cre/lox system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

In search of the tumour-suppressor functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

DCIS grading schemes and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Cell death by apoptosis during involution of the lactating breast in mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Cre-mediated gene deletion in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Insights into the functions of BRCA1 and BRCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

Inherited BRCA2 mutation associated with high grade breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Metaplastic carcinoma of the breast arising within complex sclerosing lesion: a report of five cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Active signaling by Neu in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Multiple possible sites of BRAC2 interacting with DNA repair protein RAD51

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Preneoplasia in mammary tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

"Cre"-ating mouse mutants-a meeting review on conditional mouse genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204512

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204512

1 reference

10 February 2018

PubMed ID

11494122

1 reference

10 February 2018