(Q48353007)

http://europepmc.org/abstract/MED/28902965

10 February 2018

title

Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases. (English)

1 reference

http://europepmc.org/abstract/MED/28902965

10 February 2018

author

Stefania Mirabella

1

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13 June 2020

Camilla Matassini

3

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13 June 2020

Andrea Goti

4

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13 June 2020

Inmaculada Robina

7

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13 June 2020

Antonio J Moreno-Vargas

8

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13 June 2020

Jesús Jiménez-Barbero

10

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13 June 2020

Francesca Cardona

11

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13 June 2020

author name string

Giampiero D'Adamio

2

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13 June 2020

Sandra Delgado

5

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13 June 2020

Ana Gimeno

6

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13 June 2020

Sergej Šesták

9

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13 June 2020

language of work or name

English

0 references

publication date

7 August 2017

1 reference

http://europepmc.org/abstract/MED/28902965

10 February 2018

published in

Chemistry—A European Journal

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13 June 2020

volume

23

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13 June 2020

issue

58

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13 June 2020

page(s)

14585-14596

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Multivalent inhibitors for carbohydrate-processing enzymes: beyond the "lock-and-key" concept

13 June 2020

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Characterization of jack-bean α-D-mannosidase as a zinc metalloenzyme

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Jack bean α-mannosidase: amino acid sequencing and N-glycosylation analysis of a valuable glycomics tool.

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The structure of bovine lysosomal alpha-mannosidase suggests a novel mechanism for low-pH activation

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The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.

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Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

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Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.

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6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures

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Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar.

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Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.

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The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identifiers

DOI

10.1002/CHEM.201703011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28902965%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference