(Q48355423)

10 February 2018

title

Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis (English)

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10 February 2018

amyotrophic lateral sclerosis

main subject

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6

Peter M Andersen

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10 February 2018

Karin S Graffmo

1

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10 February 2018

Karin Forsberg

2

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10 February 2018

Johan Bergh

3

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10 February 2018

Anna Birve

4

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10 February 2018

Per Zetterström

5

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10 February 2018

Stefan L Marklund

7

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10 February 2018

Thomas Brännström

8

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10 February 2018

publication date

1 October 2012

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10 February 2018

published in

Human Molecular Genetics

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10 February 2018

volume

22

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10 February 2018

issue

1

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10 February 2018

page(s)

51-60

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10 February 2018

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Mutant superoxide dismutase-1 indistinguishable from wild-type causes ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Intermolecular transmission of superoxide dismutase 1 misfolding in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

The Organization of the Forelimb Representation of the C57BL/6 Mouse Motor Cortex as Defined by Intracortical Microstimulation and Cytoarchitecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

CuZn-superoxide dismutase, extracellular superoxide dismutase, and glutathione peroxidase in blood from individuals homozygous for Asp90Ala CuZu-superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Cortical 5-HT1A receptor binding in patients with homozygous D90A SOD1 vs sporadic ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Amyotrophic lateral sclerosis with ophthalmoplegia and multisystem degeneration in patients on long-term use of respirators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Familial amyotrophic lateral sclerosis with a novel Leu126Ser mutation in the copper/zinc superoxide dismutase gene showing mild clinical features and lewy body-like hyaline inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase-linked familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS399

21 January 2018

Identifiers

DOI

10.1093/HMG/DDS399

1 reference

10 February 2018

1 reference

10 February 2018