(Q48636538)

13 February 2018

title

Lysosomal generation of amyloid beta protein species in transgenic mice (English)

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13 February 2018

author name string

Kawarabayashi T

1

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13 February 2018

Igeta Y

2

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13 February 2018

Sato M

3

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13 February 2018

Sasaki A

4

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13 February 2018

Matsubara E

5

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13 February 2018

Kanai M

6

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13 February 2018

Tomidokoro Y

7

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13 February 2018

Ishiguro K

8

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13 February 2018

Okamoto K

9

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13 February 2018

Hirai S

10

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13 February 2018

Shoji M

11

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13 February 2018

language of work or name

English

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publication date

1 August 1997

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13 February 2018

number of pages

6

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based on heuristic

inferred from page(s)

published in

Brain Research

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13 February 2018

volume

765

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13 February 2018

issue

2

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13 February 2018

page(s)

343-348

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13 February 2018

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

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Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

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Candidate .gamma.-Secretases in the Generation of the Carboxyl Terminus of the Alzheimer's Disease .beta.A4 Amyloid: Possible Involvement of Cathepsin D

7 January 2021

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Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

7 January 2021

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

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Modified amyloid beta protein ending at 42 or 40 with different solubility accumulates in the brain of Alzheimer's disease

7 January 2021

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Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.

7 January 2021

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

7 January 2021

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Accumulation of beta-amyloid fibrils in pancreas of transgenic mice

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

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7 January 2021

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

7 January 2021

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

7 January 2021

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Immunohistochemical evidence for amyloid beta in rat soleus muscle in chloroquine-induced myopathy

7 January 2021

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Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

7 January 2021

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10.1016/S0006-8993(97)00695-1

7 January 2021

Identifiers

DOI

1 reference

13 February 2018

1 reference

13 February 2018