(Q48789186)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

0 references

0 references

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

10

Marc Tessier-Lavigne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

author name string

Dylan Kwart

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Antonia Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Andrew Sproul

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Samson Jacob

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Shaun Teo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Kimberly Moore Olsen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Andrew Gregg

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Scott Noggle

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

language of work or name

English

0 references

publication date

27 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

volume

533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

issue

7601

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

page(s)

125-129

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27120160%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 April 2020

1 reference

https://scigraph.springernature.com/pub.10.1038/nature17664

0 references

cites work

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1 reference

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Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

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Multiplex genome engineering using CRISPR/Cas systems

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Inducible in vivo genome editing with CRISPR-Cas9

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CRISPR-Cas9 knockin mice for genome editing and cancer modeling

21 January 2018

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

21 January 2018

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Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

21 January 2018

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One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

21 January 2018

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Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system.

21 January 2018

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

21 January 2018

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Optimization of scarless human stem cell genome editing

21 January 2018

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Engineered CRISPR-Cas9 nucleases with altered PAM specificities

21 January 2018

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Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems

21 January 2018

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Gene conversion tracts from double-strand break repair in mammalian cells

21 January 2018

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The position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotides

21 January 2018

1 reference

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Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells

21 January 2018

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Animal models of Alzheimer's disease and frontotemporal dementia

21 January 2018

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Modeling familial Alzheimer's disease with induced pluripotent stem cells

21 January 2018

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Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

21 January 2018

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The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE17664

Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors

21 January 2018

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The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells

21 January 2018

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Small molecules enhance CRISPR genome editing in pluripotent stem cells.

21 January 2018

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Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

21 January 2018

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Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

21 January 2018

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

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Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE17664

Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE17664

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

21 January 2018

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PEAR: a fast and accurate Illumina Paired-End reAd mergeR.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE17664

Comparison of DNA sequences with protein sequences.

21 January 2018

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Manipulation of FASTQ data with Galaxy

21 January 2018

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Fast and accurate long-read alignment with Burrows-Wheeler transform

21 January 2018

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

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Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

21 January 2018

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COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

21 January 2018

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Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

21 January 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

21 January 2018

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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

21 January 2018

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12 December 2020

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12 December 2020

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

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