(Q48850008)

English

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits.

scientific article published on 11 October 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits. (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

X-linked intellectual disability

0 references

synaptic plasticity

1 reference

based on heuristic

inferred from title

disability affecting intellectual abilities

1 reference

based on heuristic

inferred from title

Hans-Peter Lipp

14

object named as

Hans-Peter Lipp

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

Kerstin Kutsche

16

object named as

Kerstin Kutsche

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

author name string

Ger J A Ramakers

1

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

David Wolfer

2

1 reference

Europe PubMed Central

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16 February 2018

http://europepmc.org/abstract/MED/21989057

Georg Rosenberger

3

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Kerstin Kuchenbecker

4

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Hans-Jürgen Kreienkamp

5

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Janine Prange-Kiel

6

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Gabriele Rune

7

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Europe PubMed Central

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http://europepmc.org/abstract/MED/21989057

Karin Richter

8

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Kristina Langnaese

9

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Sophie Masneuf

10

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Michael R Bösl

11

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Klaus-Dieter Fischer

12

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Harm J Krugers

13

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Elly van Galen

15

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

publication date

11 October 2011

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Human Molecular Genetics

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

21

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

2

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

268-286

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

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GAP control: regulating the regulators of small GTPases

1 reference

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21 January 2018

Rho GTPases and the actin cytoskeleton

1 reference

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21 January 2018

Rho GTPases and signaling networks

1 reference

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21 January 2018

The role of the Rho GTPases in neuronal development

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21 January 2018

Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity

1 reference

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21 January 2018

Actin-based plasticity in dendritic spines

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21 January 2018

Molecular mechanisms of dendritic spine morphogenesis

1 reference

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21 January 2018

Rho GTPases and activity-dependent dendrite development

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21 January 2018

Rho-linked genes and neurological disorders

1 reference

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21 January 2018

Rho GTPases, dendritic structure, and mental retardation

1 reference

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21 January 2018

Rho proteins, mental retardation and the cellular basis of cognition

1 reference

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21 January 2018

Genetics of mental retardation

1 reference

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21 January 2018

Rho proteins, mental retardation and the neurobiological basis of intelligence

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21 January 2018

Dendritic pathology in mental retardation: from molecular genetics to neurobiology.

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21 January 2018

Dendritic anomalies in disorders associated with mental retardation

1 reference

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21 January 2018

PAK3 mutation in nonsyndromic X-linked mental retardation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering

1 reference

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21 January 2018

A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

1 reference

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21 January 2018

Biology of the p21-activated kinases

1 reference

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21 January 2018

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Synaptic plasticity, memory and the hippocampus: a neural network approach to causality.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

A comparative expression analysis of four MRX genes regulating intracellular signalling via small GTPases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Long-term potentiation--a decade of progress?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment.

1 reference

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21 January 2018

Behavioural stress facilitates the induction of long-term depression in the hippocampus

1 reference

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21 January 2018

Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53.

1 reference

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21 January 2018

1 reference

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21 January 2018

The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR457

21 January 2018

Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

1 reference

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21 January 2018

Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling

1 reference

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21 January 2018

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

1 reference

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21 January 2018

Pten regulates neuronal arborization and social interaction in mice

1 reference

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21 January 2018

Dendritic arbor development and synaptogenesis

1 reference

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21 January 2018

Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior

1 reference

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21 January 2018

Social behavior and cortisol reactivity in children with fragile X syndrome

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21 January 2018

Advances in research on the fragile X syndrome

1 reference

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21 January 2018

Further delineation of the executive deficit in males with fragile-X syndrome.

1 reference

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21 January 2018

A role for monomeric G-proteins in synaptic plasticity in the rat dentate gyrus in vitro

1 reference

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21 January 2018

Enhancement of learning and memory after activation of cerebral Rho GTPases

1 reference

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21 January 2018

A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation.

1 reference

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21 January 2018

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

1 reference

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21 January 2018

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

1 reference

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21 January 2018

Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase

1 reference

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21 January 2018

Regulation of receptor-mediated endocytosis by Rho and Rac.

1 reference

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21 January 2018

Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation

1 reference

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21 January 2018

The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1

1 reference

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21 January 2018

The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins

1 reference

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21 January 2018

Endocytosis and intracellular trafficking of ErbBs

1 reference

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21 January 2018

Cbl promotes clustering of endocytic adaptor proteins.

1 reference

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21 January 2018

Activated Cdc42 Sequesters c-Cbl and Prevents EGF Receptor Degradation

1 reference

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Rho GTPases: role in dendrite and axonal growth, mental retardation, and axonal regeneration

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AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling

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21 January 2018

Analysis of thick brain sections by obverse—Reverse computer microscopy: Application of a new, high clarity Golgi—Nissl stain

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Stereology, morphometry, and mapping: the whole is greater than the sum of its parts

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21 January 2018

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

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Median raphe mediates estrogenic effects to the hippocampus in female rats

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Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat.

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The impact of recent stereological advances on quantitative studies of the nervous system

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Isolation and characterization of postsynaptic densities from various brain regions: enrichment of different types of postsynaptic densities

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Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin

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Identifiers

10.1093/HMG/DDR457

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/21989057

ResearchGate publication ID

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