(Q48939073)

17 February 2018

title

Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load. (English)

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17 February 2018

12

Charles Duyckaerts

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17 February 2018

author name string

Dominique Santiard-Baron

1

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17 February 2018

Dominique Langui

2

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17 February 2018

Maryse Delehedde

3

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17 February 2018

Benoît Delatour

4

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17 February 2018

Brigitte Schombert

5

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17 February 2018

Nathalie Touchet

6

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17 February 2018

Günter Tremp

7

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17 February 2018

Marie-Françoise Paul

8

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17 February 2018

Véronique Blanchard

9

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17 February 2018

Nicolas Sergeant

10

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17 February 2018

André Delacourte

11

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17 February 2018

Laurent Pradier

13

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17 February 2018

Luc Mercken

14

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17 February 2018

language of work or name

English

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publication date

1 April 2005

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17 February 2018

Journal of Neurochemistry

published in

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17 February 2018

volume

93

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17 February 2018

issue

2

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17 February 2018

page(s)

330-338

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17 February 2018

Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid

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1 reference

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The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 January 2018

1 reference

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cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

21 January 2018

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Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

21 January 2018

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Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.

21 January 2018

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Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1

21 January 2018

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Secretases as targets for the treatment of Alzheimer's disease

21 January 2018

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Proteolytical processing of mutated human amyloid precursor protein in transgenic mice.

21 January 2018

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FE65 in Alzheimer's disease: neuronal distribution and association with neurofibrillary tangles

21 January 2018

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Secretases as therapeutic targets for the treatment of Alzheimer's disease

21 January 2018

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Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

21 January 2018

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The DNA sequence encompassing the transcription start site of a TATA-less promoter contains enough information to drive neuron-specific transcription

21 January 2018

1 reference

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The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

hFE65L influences amyloid precursor protein maturation and secretion

21 January 2018

1 reference

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Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex

21 January 2018

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

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Secretases as targets for drug design in Alzheimer's disease

21 January 2018

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The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type

21 January 2018

1 reference

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Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Expression of the Fe65 adapter protein in adult and developing mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

APP processing is regulated by cytoplasmic phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice.

21 January 2018

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Potential novel targets for Alzheimer pharmacotherapy: I. Secretases

21 January 2018

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Regulation of amyloid precursor protein cleavage.

21 January 2018

1 reference

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The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Progressive decrease of amyloid precursor protein carboxy terminal fragments (APP-CTFs), associated with tau pathology stages, in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Isoform-specific knockout of FE65 leads to impaired learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03026.X

10.1111/J.1471-4159.2005.03026.X

21 January 2018

Identifiers

DOI

1 reference

17 February 2018

PubMed ID

15816856

1 reference

17 February 2018