(Q48959837)

2 July 2019

title

FANCD2 protects against bone marrow injury from ferroptosis. (English)

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2 July 2019

regulation of ferroptosis

main subject

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6

Michael W Epperly

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2 July 2019

Xinxin Song

1

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2 July 2019

Yangchun Xie

2

1 reference

2 July 2019

Rui Kang

3

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2 July 2019

Wen Hou

4

1 reference

2 July 2019

Xiaofang Sun

5

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2 July 2019

Joel S Greenberger

7

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2 July 2019

Daolin Tang

8

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2 July 2019

language of work or name

English

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publication date

20 October 2016

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2 July 2019

Biochemical and Biophysical Research Communications

published in

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2 July 2019

volume

480

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2 July 2019

issue

3

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2 July 2019

page(s)

443-449

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2 July 2019

Regulated cell death: signaling and mechanisms

cites work

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

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Cancer therapy-induced residual bone marrow injury-Mechanisms of induction and implication for therapy

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Ferroptosis: process and function

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Ferroptosis: an iron-dependent form of nonapoptotic cell death

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Regulation of ferroptotic cancer cell death by GPX4

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The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

9 October 2020

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Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells

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Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib

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Interaction of FANCD2 and NBS1 in the DNA damage response

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Positional cloning of a novel Fanconi anemia gene, FANCD2

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Intraesophageal manganese superoxide dismutase-plasmid liposomes ameliorates novel total-body and thoracic radiation sensitivity of NOS1-/- mice

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Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Endogenous HMGB1 regulates autophagy

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Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy.

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Ferroptosis is an autophagic cell death process

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Autophagy promotes ferroptosis by degradation of ferritin

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An essential role for functional lysosomes in ferroptosis of cancer cells.

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9 October 2020

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Ferroptosis as a p53-mediated activity during tumour suppression

9 October 2020

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Identification of ACSL4 as a biomarker and contributor of ferroptosis

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation.

9 October 2020

1 reference

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Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

HSPB1 as a novel regulator of ferroptotic cancer cell death

9 October 2020

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System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.

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FANCD2 activates transcription of TAp63 and suppresses tumorigenesis

9 October 2020

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The DNA damage-induced cell death response: a roadmap to kill cancer cells

9 October 2020

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Stress and DNA repair biology of the Fanconi anemia pathway

9 October 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

9 October 2020

1 reference

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Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(-/-) (C57BL/6) Mice

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

The role of iron and reactive oxygen species in cell death

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

The molecular biology of human iron metabolism

9 October 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591579

10.1016/J.BBRC.2016.10.068

9 October 2020

Identifiers

DOI

1 reference

2 July 2019

PMCID

6591579

1 reference

2 July 2019

PubMed ID

27773819

1 reference

2 July 2019