(Q49109048)

18 February 2018

title

IDH1 mutations in grade II astrocytomas are associated with unfavorable progression-free survival and prolonged postrecurrence survival. (English)

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18 February 2018

5

Joerg-Christian Tonn

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18 February 2018

author name string

Niklas Thon

1

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18 February 2018

Sabina Eigenbrod

2

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18 February 2018

Simone Kreth

3

1 reference

18 February 2018

Juergen Lutz

4

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18 February 2018

Hans Kretzschmar

6

1 reference

18 February 2018

Aurelia Peraud

7

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18 February 2018

Friedrich-Wilhelm Kreth

8

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18 February 2018

language of work or name

English

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publication date

29 June 2011

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18 February 2018

number of pages

9

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inferred from page(s)

published in

Cancer

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18 February 2018

volume

118

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18 February 2018

issue

2

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18 February 2018

page(s)

452-460

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18 February 2018

Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Molecular classification of low-grade diffuse gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 and IDH2 mutations in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 mutations in gliomas: when an enzyme loses its grip

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Expression of hypoxia-inducible factor 1? in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Prognostic impact of TP53 mutation status for adult patients with supratentorial World Health Organization Grade II astrocytoma or oligoastrocytoma: a long-term analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

Nonparametric Estimation from Incomplete Observations

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

Expression and mutagenesis of mammalian cytosolic NADP+-specific isocitrate dehydrogenase

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review

21 January 2018

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https://api.crossref.org/works/10.1002%2FCNCR.26298

D-2-Hydroxyglutaric aciduria: unravelling the biochemical pathway and the genetic defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

7 January 2021

Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

7 January 2021

Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

7 January 2021

Identification by mutagenesis of arginines in the substrate binding site of the porcine NADP-dependent isocitrate dehydrogenase

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.26298

7 January 2021

Identifiers

DOI

10.1002/CNCR.26298

1 reference

18 February 2018

1 reference

18 February 2018