(Q49121379)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Elizabeth W Bradley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Mikolaj Ogrodnik

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Diana Jurk

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

11

Val Lowe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

14

James L Kirkland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

12

Tamar Tchkonia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

5

Tamar Pirtskhalava

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

3

Megan M Weivoda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Soyun M Hwang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Teresa Decklever

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Geoffry L Curran

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Kurt O Johnson

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Jennifer J Westendorf

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

language of work or name

English

0 references

publication date

1 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

number of pages

6

1 reference

The Journals of Gerontology

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

72

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

780-785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

Ageing and the pathogenesis of osteoarthritis.

20 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Targeting senescent cells enhances adipogenesis and metabolic function in old age

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Safety and efficacy of paracetamol and NSAIDs in osteoarthritis: which drug to recommend?

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Chondrosenescence: definition, hallmarks and potential role in the pathogenesis of osteoarthritis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Emerging regulators of the inflammatory process in osteoarthritis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

The epidemiology of osteoarthritis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Mouse models of osteoarthritis: modelling risk factors and assessing outcomes.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

A senescent cell bystander effect: senescence-induced senescence

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

The role of mitochondria in osteoarthritis

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Quantitative assessment of tactile allodynia in the rat paw

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Senescent human fibroblasts show increased glycolysis and redox homeostasis with extracellular metabolomes that overlap with those of irreparable DNA damage, aging, and disease.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Osteoarthritis cartilage histopathology: grading and staging.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Synovial tissue inflammation in early and late osteoarthritis

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Telomere erosion and senescence in human articular cartilage chondrocytes.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861939

Glycosaminoglycan sulfation in human osteoarthritis. Disease-related alterations at the non-reducing termini of chondroitin and dermatan sulfate

14 August 2018

1 reference

12 December 2020

DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes

1 reference

12 December 2020

The role of chondrocyte senescence in osteoarthritis

1 reference

12 December 2020

DNA damage response and cellular senescence in tissues of aging mice

1 reference

12 December 2020

Identifiers

DOI

10.1093/GERONA/GLW154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516624%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

27516624

1 reference