(Q49843616)

English

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma.

scientific article published on 19 February 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

3 references

6 August 2020

5 July 2021

28 October 2022

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma. (English)

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

pancreatic ductal carcinoma

3 references

6 August 2020

5 July 2021

28 October 2022

pancreatic neoplasm

3 references

6 August 2020

5 July 2021

28 October 2022

pancreatic stellate cells

1 reference

12 October 2019

paracrine signaling

1 reference

6 August 2020

energy metabolism

2 references

PubMed publication ID

5 July 2021

1 reference

PubMed publication ID

author name string

Yaojie Fu

1

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

Shanshan Liu

2

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

Shan Zeng

3

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

Hong Shen

4

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

language of work or name

1 reference

based on heuristic

inferred from title

publication date

19 February 2018

8 references

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

21 March 2019

24 March 2019

3 April 2019

12 October 2019

6 August 2020

5 July 2021

28 October 2022

Molecular Cancer

8 references

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

21 March 2019

24 March 2019

3 April 2019

12 October 2019

6 August 2020

5 July 2021

28 October 2022

17

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

1

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

62

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

copyright license

Creative Commons Attribution 4.0 International

7 references

Europe PubMed Central

21 March 2019

Europe PubMed Central

24 March 2019

Europe PubMed Central

3 April 2019

Europe PubMed Central

12 October 2019

Europe PubMed Central

6 August 2020

Europe PubMed Central

5 July 2021

Europe PubMed Central

28 October 2022

copyright status

0 references

on focus list of Wikimedia project

0 references

https://scigraph.springernature.com/pub.10.1186/s12943-018-0815-z

0 references

The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy.

1 reference

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Pancreatic stellate cells in pancreatic cancer: In focus

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Pancreatic stellate cells: what's new?

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Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy.

1 reference

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1 reference

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1 reference

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Pancreatic stellate cells increase pancreatic cancer cells invasion through the hepatocyte growth factor /c-Met/survivin regulated by P53/P21.

1 reference

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Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis.

1 reference

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Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.

1 reference

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14 June 2018

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

1 reference

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14 June 2018

Crosstalk between stromal cells and cancer cells in pancreatic cancer: New insights into stromal biology

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Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer

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14 June 2018

Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice

1 reference

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14 June 2018

Kindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer

1 reference

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14 June 2018

Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma.

1 reference

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14 June 2018

MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1α) in the tumor microenvironments

1 reference

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14 June 2018

Cancer Statistics, 2017.

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14 June 2018

Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters.

1 reference

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14 June 2018

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors.

1 reference

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14 June 2018

Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer

1 reference

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14 June 2018

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

1 reference

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14 June 2018

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

1 reference

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14 June 2018

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

1 reference

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14 June 2018

ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion

1 reference

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14 June 2018

The biology and function of fibroblasts in cancer

1 reference

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14 June 2018

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

1 reference

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14 June 2018

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

1 reference

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14 June 2018

Targeting tumor tolerance: A new hope for pancreatic cancer therapy?

1 reference

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14 June 2018

Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Periostin promotes tumor angiogenesis in pancreatic cancer via Erk/VEGF signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer

1 reference

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14 June 2018

Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

1 reference

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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

1 reference

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Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

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14 June 2018

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Paracrine SDF-1α signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells

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14 June 2018

Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreatic cancer

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14 June 2018

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MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies

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Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium.

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

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14 June 2018

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer.

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14 June 2018

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

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14 June 2018

Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes

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14 June 2018

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

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14 June 2018

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

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14 June 2018

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

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14 June 2018

A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma

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14 June 2018

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

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14 June 2018

Tumour-stroma interactions in pancreatic ductal adenocarcinoma: rationale and current evidence for new therapeutic strategies

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14 June 2018

miR-210 regulates the interaction between pancreatic cancer cells and stellate cells

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14 June 2018

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

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14 June 2018

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner

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14 June 2018

Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Mechanical compression drives cancer cells toward invasive phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Plasma 25-hydroxyvitamin D and risk of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Organ-, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Albumin mediates PPAR-gamma or C/EBP-alpha-induced phenotypic changes in pancreatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Signal transduction in pancreatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Periostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Pancreatic stellate cells: partners in crime with pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Cytokines and peroxisome proliferator-activated receptor gamma ligand regulate phagocytosis by pancreatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 June 2018

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Stromal cues regulate the pancreatic cancer epigenome and metabolome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

TGF-β-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

16 June 2018

Coenzyme Q10 inhibits the activation of pancreatic stellate cells through PI3K/AKT/mTOR signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal Adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Rational combinations of immunotherapy for pancreatic ductal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

IL6 Receptor Blockade Enhances Chemotherapy Efficacy in Pancreatic Ductal Adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Current and Emerging Therapies in Metastatic Pancreatic Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Strategies for Increasing Pancreatic Tumor Immunogenicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Exosome-Mediated Intercellular Communication Between Stellate Cells and Cancer Cells in Pancreatic Ductal Adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Exosomes Derived From Pancreatic Stellate Cells: MicroRNA Signature and Effects on Pancreatic Cancer Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Heterogeneous Stromal Signaling within the Tumor Microenvironment Controls the Metastasis of Pancreatic Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Genetics and Biology of Pancreatic Ductal Adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Monocytes infiltrate the pancreas via the MCP-1/CCR2 pathway and differentiate into stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Periostin, a matrix specific protein, is associated with proliferation and invasion of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Tocotrienols induce apoptosis and autophagy in rat pancreatic stellate cells through the mitochondrial death pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Galectin-1 induces chemokine production and proliferation in pancreatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Identification, culture, and characterization of pancreatic stellate cells in rats and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

14 August 2018

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5817854

30 November 2018

The hedgehog pathway and pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloid-derived suppressor cells attenuate TH1 development through IL-6 production to promote tumor progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The carcinoma-associated fibroblast expressing fibroblast activation protein and escape from immune surveillance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29458370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12943-018-0815-Z

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12943-018-0815-z

release_4zzmsor2a5amhnq7lubs46r2rq

1 reference

https://api.fatcat.wiki/v0/release/4zzmsor2a5amhnq7lubs46r2rq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 June 2018

http://europepmc.org/abstract/PMC/5817854

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