(Q50001782)

23 February 2018

title

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. (English)

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23 February 2018

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18

François Spitz

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23 February 2018

Andreas Trumpp

17

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John Dick

John E Dick

16

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Amir Giladi

13

Ido Amit

1 reference

23 February 2018

Peter W Zandstra

14

Peter W Zandstra

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23 February 2018

Mathieu Lupien

15

Mathieu Lupien

1 reference

23 February 2018

Alex Murison

7

Alex Murison

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23 February 2018

author name string

Carsten Bahr

1

1 reference

23 February 2018

Lisa von Paleske

2

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23 February 2018

Veli V Uslu

3

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23 February 2018

Silvia Remeseiro

4

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23 February 2018

Naoya Takayama

5

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23 February 2018

Stanley W Ng

6

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23 February 2018

Katja Langenfeld

8

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23 February 2018

Massimo Petretich

9

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23 February 2018

Roberta Scognamiglio

10

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23 February 2018

Petra Zeisberger

11

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23 February 2018

Amelie S Benk

12

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23 February 2018

language of work or name

English

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publication date

17 January 2018

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23 February 2018

published in

Nature

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23 February 2018

volume

553

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23 February 2018

issue

7689

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23 February 2018

page(s)

515-520

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23 February 2018

https://scigraph.springernature.com/pub.10.1038/nature25193

exact match

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cites work

Myc roles in hematopoiesis and leukemia

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Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

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c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

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Long-range enhancers regulating Myc expression are required for normal facial morphogenesis

21 January 2018

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A map of the cis-regulatory sequences in the mouse genome

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8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

21 January 2018

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A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

21 January 2018

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia

21 January 2018

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Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

21 January 2018

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Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

21 January 2018

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Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C.

21 January 2018

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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

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Systematic mapping of functional enhancer-promoter connections with CRISPR interference

21 January 2018

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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

21 January 2018

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c-Myc regulates mammalian body size by controlling cell number but not cell size

21 January 2018

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c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors

21 January 2018

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Immunogenetics. Chromatin state dynamics during blood formation

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Multiple loci are associated with white blood cell phenotypes

21 January 2018

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Identification of nine novel loci associated with white blood cell subtypes in a Japanese population

21 January 2018

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High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

21 January 2018

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Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

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Stem cell gene expression programs influence clinical outcome in human leukemia.

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A 17-gene stemness score for rapid determination of risk in acute leukaemia.

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The transcriptional program of a human B cell line in response to Myc

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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

21 January 2018

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A regulatory archipelago controls Hox genes transcription in digits

21 January 2018

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An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape.

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21 January 2018

Locus control regions

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DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

21 January 2018

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis

21 January 2018

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21 January 2018

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21 January 2018

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The Molecular Signatures Database (MSigDB) hallmark gene set collection

21 January 2018

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A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE25193

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21 January 2018

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21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE25193

1 reference

23 February 2018

PubMed ID

29342133

1 reference

23 February 2018