(Q50200755)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Development of a pre-glycoengineered CHO-K1 host cell line for the expression of antibodies with enhanced Fc mediated effector function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Oliver Plöttner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

3

Jörg Zielonka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

author name string

Oliver Popp

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Samuel Moser

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Silke Hansen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

publication date

12 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

published in

Monoclonal Antibodies

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

page(s)

290-303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

4 April 2020

copyright license

start time

12 December 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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The current status and prospects of antibody engineering for therapeutic use: focus on glycoengineering technology

30 June 2018

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30 June 2018

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High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer

30 June 2018

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IgG-Fc N-glycosylation at Asn297 and IgA O-glycosylation in the hinge region in health and disease

30 June 2018

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30 June 2018

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Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans

30 June 2018

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30 June 2018

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Isotype and glycoform selection for antibody therapeutics

30 June 2018

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Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines

30 June 2018

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Effects of cell culture conditions on antibody N-linked glycosylation--what affects high mannose 5 glycoform

30 June 2018

1 reference

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A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies

30 June 2018

1 reference

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High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans

30 June 2018

1 reference

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Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactose

30 June 2018

1 reference

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The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo

30 June 2018

1 reference

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Mammalian cell transfection: the present and the future

30 June 2018

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A novel role for the IgG Fc glycan: the anti-inflammatory activity of sialylated IgG Fcs.

30 June 2018

1 reference

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Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Production of therapeutic antibodies with controlled fucosylation

30 June 2018

1 reference

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Optimal and consistent protein glycosylation in mammalian cell culture

30 June 2018

1 reference

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Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies

30 June 2018

1 reference

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A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?

30 June 2018

1 reference

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Terminal sugars of Fc glycans influence antibody effector functions of IgGs

30 June 2018

1 reference

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Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function

30 June 2018

1 reference

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The impact of glycosylation on the biological function and structure of human immunoglobulins.

30 June 2018

1 reference

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Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

30 June 2018

1 reference

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Comparison of cell lines for stable production of fucose-negative antibodies with enhanced ADCC.

30 June 2018

1 reference

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Modulation of therapeutic antibody effector functions by glycosylation engineering: influence of Golgi enzyme localization domain and co-expression of heterologous beta1, 4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II.

30 June 2018

1 reference

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Fucose removal from complex-type oligosaccharide enhances the antibody-dependent cellular cytotoxicity of single-gene-encoded antibody comprising a single-chain antibody linked the antibody constant region

30 June 2018

1 reference

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Improved effector functions of a therapeutic monoclonal Lewis Y-specific antibody by glycoform engineering

30 June 2018

1 reference

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Glycosylation of recombinant antibody therapeutics

30 June 2018

1 reference

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Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity

30 June 2018

1 reference

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The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

30 June 2018

1 reference

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

30 June 2018

1 reference

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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

30 June 2018

1 reference

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A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis

30 June 2018

1 reference

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A fluorescent assay method for GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha 1-6fucosyltransferase activity, involving high performance liquid chromatography

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

The glycosylation of antibody molecules: functional significance.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

The Chinese hamster ovary glycosylation mutants LEC11 and LEC12 express two novel GDP-fucose:N-acetylglucosaminide 3-alpha-L-fucosyltransferase enzymes

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab

30 June 2018

1 reference

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Marketed therapeutic antibodies compendium

14 August 2018

1 reference

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Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells.

14 August 2018

1 reference

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Amino acid and manganese supplementation modulates the glycosylation state of erythropoietin in a CHO culture system.

14 August 2018

1 reference

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Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825202

Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29173063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Advances in the assessment and control of the effector functions of therapeutic antibodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29173063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Monoclonal antibodies in cancer therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29173063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/19420862.2017.1405203

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29173063%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

29173063

1 reference