(Q50317337)

3 March 2018

title

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer. (English)

1 reference

3 March 2018

author

Victor Velculescu

29

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3 March 2018

Hyunseok Kang

object named as

Hyunseok Kang

15

0 references

author name string

Valsamo Anagnostou

1

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3 March 2018

Kellie N Smith

2

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3 March 2018

Patrick M Forde

3

1 reference

3 March 2018

Noushin Niknafs

4

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3 March 2018

Rohit Bhattacharya

5

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3 March 2018

James White

6

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3 March 2018

Theresa Zhang

7

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3 March 2018

Vilmos Adleff

8

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3 March 2018

Jillian Phallen

9

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3 March 2018

Neha Wali

10

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3 March 2018

Carolyn Hruban

11

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3 March 2018

Violeta B Guthrie

12

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3 March 2018

Kristen Rodgers

13

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3 March 2018

Jarushka Naidoo

14

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3 March 2018

William Sharfman

16

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3 March 2018

Christos Georgiades

17

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3 March 2018

Franco Verde

18

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3 March 2018

Peter Illei

19

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3 March 2018

Qing Kay Li

20

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3 March 2018

Edward Gabrielson

21

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3 March 2018

Malcolm V Brock

22

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3 March 2018

Cynthia A Zahnow

23

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3 March 2018

Stephen B Baylin

24

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3 March 2018

Robert B Scharpf

25

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3 March 2018

Julie R Brahmer

26

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3 March 2018

Rachel Karchin

27

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3 March 2018

Drew M Pardoll

28

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3 March 2018

publication date

28 December 2016

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3 March 2018

published in

Cancer Discovery

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3 March 2018

volume

7

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3 March 2018

issue

3

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3 March 2018

page(s)

264-276

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3 March 2018

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

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Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

22 May 2018

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

22 May 2018

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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

22 May 2018

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SubClonal Hierarchy Inference from Somatic Mutations: Automatic Reconstruction of Cancer Evolutionary Trees from Multi-region Next Generation Sequencing

22 May 2018

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The genomic landscape of response to EGFR blockade in colorectal cancer.

22 May 2018

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Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

22 May 2018

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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Adaptive Immune Resistance: How Cancer Protects from Immune Attack

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer

22 May 2018

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Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer

22 May 2018

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Pembrolizumab for the treatment of non-small-cell lung cancer

22 May 2018

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Personalized genomic analyses for cancer mutation discovery and interpretation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Neoantigens in cancer immunotherapy.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

PD-1 blockade induces responses by inhibiting adaptive immune resistance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Genetic basis for clinical response to CTLA-4 blockade in melanoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

OptiType: precision HLA typing from next-generation sequencing data

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygosity

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Signatures of mutational processes in human cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

22 May 2018

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Comprehensive genomic characterization of squamous cell lung cancers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Heterochromatin and the DNA damage response: the need to relax

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

NetCTLpan: pan-specific MHC class I pathway epitope predictions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Comparative lesion sequencing provides insights into tumor evolution

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

How TCRs bind MHCs, peptides, and coreceptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

SYFPEITHI: database for MHC ligands and peptide motifs

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Loss of a unique tumor antigen by cytotoxic T lymphocyte immunoselection from a 3-methylcholanthrene-induced mouse sarcoma reveals secondary unique and shared antigens

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

A general method applicable to the search for similarities in the amino acid sequence of two proteins

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Using synthetic templates to design an unbiased multiplex PCR assay.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

Epitope landscape in breast and colorectal cancer.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5733805

10.1158/2159-8290.CD-16-0828

14 August 2018

Identifiers

DOI

1 reference

3 March 2018

PMCID

5733805

1 reference

3 March 2018

PubMed ID

28031159

1 reference

3 March 2018