(Q50459138)

English

p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis.

scientific article published in February 2007

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scholarly article

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/17287518

p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

Martine F Roussel

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

author name string

Heidi Laine

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

Angelika Doetzlhofer

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

Johanna Mantela

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

Jukka Ylikoski

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

Marikki Laiho

5

1 reference

Europe PubMed Central

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11 May 2020

Neil Segil

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

Ulla Pirvola

8

1 reference

Europe PubMed Central

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11 May 2020

language of work or name

0 references

publication date

1 February 2007

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/17287518

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

27

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

1434-1444

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

INK4d-deficient mice are fertile despite testicular atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the developing rat cochlea and its related structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle inhibitors: three families united by a common cause

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase inhibitors in the development of the central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live or let die: the cell's response to p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasomal activity modulates TGF-ss signaling in a gene-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress, cell cycle, and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pifithrin-alpha suppresses p53 and protects cochlear and vestibular hair cells from cisplatin-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle molecules and vertebrate neuron death: E2F at the hub.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arf tumor suppressor promoter monitors latent oncogenic signals in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle activation linked to neuronal cell death initiated by DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle regulation of neuronal apoptosis in development and disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and genomic instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divide and die: cell cycle events as triggers of nerve cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle checkpoints and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to the mouse p19(Arf) tumor suppressor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 in neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regeneration and replacement in the vertebrate inner ear.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of oxidative stress in noise-induced hearing loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Prox1 during mouse cochlear development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of retinoblastoma protein in mammalian hair cell development and hearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guinea-Pig Hair Cell Pathology from Ototoxic Antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the inner ear of the mouse: a radioautographic study of terminal mitoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The retinoblastoma protein and cell cycle control

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unconventional myosins in inner-ear sensory epithelia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4956-06.2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673588&resulttype=core&format=json

11 May 2020

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