(Q50522603)

14 March 2018

title

Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling. (English)

1 reference

14 March 2018

heptaketide hydrolyase ayg1

main subject

1 reference

GeneDB

1,3,6,8-tetrahydroxynaphthalene reductase arp2

5 February 2019

1 reference

GeneDB

conidial pigment polyketide synthase alb1

5 February 2019

1 reference

5 February 2019

1 reference

6 February 2019

Conidial pigment polyketide synthase

0 references

1 reference

1 reference

3

Axel A Brakhage

1 reference

14 March 2018

author name string

Katrin Volling

series ordinal

1

1 reference

14 March 2018

Andreas Thywissen

series ordinal

2

1 reference

14 March 2018

Hans Peter Saluz

series ordinal

4

1 reference

14 March 2018

publication date

31 May 2011

1 reference

14 March 2018

published in

Cellular Microbiology

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14 March 2018

volume

13

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14 March 2018

issue

8

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14 March 2018

page(s)

1130-1148

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14 March 2018

Surface hydrophobin prevents immune recognition of airborne fungal spores

cites work

1 reference

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Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load.

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway.

21 January 2018

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Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family

21 January 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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Aspergillus fumigatus conidia inhibit tumour necrosis factor- or staurosporine-induced apoptosis in epithelial cells.

21 January 2018

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Receptor-mediated choreography of life and death.

21 January 2018

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Effect of chloroquine on phagolysosomal fusion in cultured guinea pig alveolar macrophages: implications in drug delivery

21 January 2018

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

21 January 2018

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LaeA, a regulator of morphogenetic fungal virulence factors.

21 January 2018

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Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro.

21 January 2018

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Systemic Fungal Infections Caused by Aspergillus Species: Epidemiology, Infection Process and Virulence Determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Aspergillus fumigatus conidial pigment and cAMP signal transduction: significance for virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Interaction of phagocytes with filamentous fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Anti-apoptotic genes in the survival of monocytic cells during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Signalling apoptosis: a radical approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

PI3K-dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short-lived monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Triggering and modulation of apoptosis by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Functional genomics of innate host defense molecules in normal human monocytes in response to Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

High-resolution cell surface dynamics of germinating Aspergillus fumigatus conidia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Fas-stimulated generation of reactive oxygen species or exogenous oxidative stress sensitize cells to Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

The multiple roles of Fas ligand in the pathogenesis of infectious diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Effects of conidia of various Aspergillus species on apoptosis of human pneumocytes and bronchial epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Differential effects of invasion by and phagocytosis of Salmonella typhimurium on apoptosis in human macrophages: potential role of Rho-GTPases and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

PI3K/Akt signalling pathway and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Regulation of monocytes and macrophages cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Apoptotic pathways: paper wraps stone blunts scissors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Ammonium chloride, an inhibitor of phagosome-lysosome fusion in macrophages, concurrently induces phagosome-endosome fusion, and opens a novel pathway: studies of a pathogenic mycobacterium and a nonpathogenic yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Inhibition of phagosome-lysosome fusion in macrophages by certain mycobacteria can be explained by inhibition of lysosomal movements observed after phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Aspergillus fumigatus: principles of pathogenesis and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Candida albicans phospholipomannan promotes survival of phagocytosed yeasts through modulation of bad phosphorylation and macrophage apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Reactive oxygen species and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Pathogenic roles for fungal melanins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Interaction of human phagocytes with pigmentless Aspergillus conidia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

PKSP-dependent reduction of phagolysosome fusion and intracellular kill of Aspergillus fumigatus conidia by human monocyte-derived macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

PI3K-Akt signaling and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Nuclear factor-kappaB: its role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Manipulation of host cell death pathways during microbial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Biosynthesis of fungal melanins and their importance for human pathogenic fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

The pathobiology of Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Color me bad: microbial pigments as virulence factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Targeting the PI3K/Akt Cell Survival Pathway to Induce Cell Death of HIV-1 Infected Macrophages with Alkylphospholipid Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Characterisation of the phagocytic uptake of Aspergillus fumigatus conidia by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Lysosomes: fusion and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Breaking the mitochondrial barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Improved outcomes associated with advances in therapy for invasive fungal infections in immunocompromised hosts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Fungal killing by mammalian phagocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Expression of genes in normal human monocytes in response to Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Photoprotection of human retinal pigment epithelium cells against blue light-induced apoptosis by melanin free radicals from Sepia officinalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Nuclear factor-kappaB activation: a question of life or death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Apoptosis: controlled demolition at the cellular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Coxiella burnetii inhibits apoptosis in human THP-1 cells and monkey primary alveolar macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5'-monophosphate decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Apoptosis paves the detour path for CD8 T cell activation against intracellular bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

The BCL-2 protein family: opposing activities that mediate cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Production of melanin by Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Dendritic Cells Transport Conidia and Hyphae of Aspergillus fumigatus from the Airways to the Draining Lymph Nodes and Initiate Disparate Th Responses to the Fungus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Free Radicals in Biological Materials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01605.X

10.1111/J.1462-5822.2011.01605.X

21 January 2018

Identifiers

DOI

1 reference

14 March 2018

1 reference

14 March 2018