(Q50882019)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

0 references

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

13

David E Fisher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

19

W Nicholas Haining

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

16

David E Root

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

18

John G Doench

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

author name string

Robert T Manguso

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Hans W Pope

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Margaret D Zimmer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Flavian D Brown

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Kathleen B Yates

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Natalie B Collins

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Kevin Bi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Martin W LaFleur

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Vikram R Juneja

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Sarah A Weiss

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Jennifer Lo

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Diana Miao

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Eliezer Van Allen

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Arlene H Sharpe

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

language of work or name

English

0 references

publication date

19 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

volume

547

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

issue

7664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

page(s)

413-418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

25 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5924693/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5924693/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature23270

0 references

cites work

Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

TC-PTP and PTP1B: Regulating JAK-STAT signaling, controlling lymphoid malignancies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

The Molecular Signatures Database (MSigDB) hallmark gene set collection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Interactions between HLA-G and HLA-E in Physiological and Pathological Conditions

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Genome-scale CRISPR-Cas9 knockout screening in human cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Nivolumab plus ipilimumab in advanced melanoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

IL-12-dependent inducible expression of the CD94/NKG2A inhibitory receptor regulates CD94/NKG2C+ NK cell function

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Circular binary segmentation for the analysis of array-based DNA copy number data

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

B7-H4, a molecule of the B7 family, negatively regulates T cell immunity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

GM-CSF-secreting melanoma vaccines

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Functional Genomic Characterization of Cancer Genomes.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

Analysis of regulatory CD8 T cells in Qa-1-deficient mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

CD94-NKG2A receptors regulate antiviral CD8(+) T cell responses.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5924693

14 August 2018

Identifiers

DOI

10.1038/NATURE23270

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28723893%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference