(Q38152946)

29 August 2017

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death (English)

1 reference

29 August 2017

1 reference

Dimitry Ofengeim

1

1 reference

29 August 2017

Junying Yuan

series ordinal

2

1 reference

29 August 2017

16 October 2013

1 reference

Nature Reviews Molecular Cell Biology

29 August 2017

1 reference

29 August 2017

14

1 reference

29 August 2017

11

1 reference

29 August 2017

727-736

1 reference

https://scigraph.springernature.com/pub.10.1038/nrm3683

29 August 2017

0 references

cites work

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

A novel role for RIP1 kinase in mediating TNFα production

21 January 2018

1 reference

Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

1 reference

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

TNF-alpha induces two distinct caspase-8 activation pathways

21 January 2018

1 reference

Necroptosis as an alternative form of programmed cell death

21 January 2018

1 reference

NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death

21 January 2018

1 reference

21 January 2018

IAPs: guardians of RIPK1

1 reference

Structural basis of RIP1 inhibition by necrostatins

21 January 2018

1 reference

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

1 reference

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

21 January 2018

1 reference

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

21 January 2018

1 reference

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

21 January 2018

1 reference

Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.

21 January 2018

1 reference

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

21 January 2018

1 reference

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

21 January 2018

1 reference

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

21 January 2018

1 reference

The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

1 reference

Formation of the death domain complex between FADD and RIP1 proteins in vitro

21 January 2018

1 reference

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

21 January 2018

1 reference

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

1 reference

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

21 January 2018

1 reference

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

1 reference

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

21 January 2018

1 reference

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

21 January 2018

1 reference

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

1 reference

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

1 reference

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

1 reference

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

21 January 2018

1 reference

RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

21 January 2018

1 reference

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

21 January 2018

1 reference

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

1 reference

A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling

21 January 2018

1 reference

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

21 January 2018

1 reference

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

21 January 2018

1 reference

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

21 January 2018

1 reference

Ubiquitin makes its mark on immune regulation

21 January 2018

1 reference

Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins

21 January 2018

1 reference

Systematic and quantitative assessment of the ubiquitin-modified proteome

21 January 2018

1 reference

Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

1 reference

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

21 January 2018

1 reference

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

21 January 2018

1 reference

Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

21 January 2018

1 reference

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

1 reference

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

21 January 2018

1 reference

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

1 reference

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

21 January 2018

1 reference

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

1 reference

Linear ubiquitination: a newly discovered regulator of cell signalling

21 January 2018

1 reference

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

21 January 2018

1 reference

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

21 January 2018

1 reference

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

1 reference

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

1 reference

NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling

21 January 2018

1 reference

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

21 January 2018

1 reference

The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay

21 January 2018

1 reference

A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis

21 January 2018

1 reference

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

21 January 2018

1 reference

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

21 January 2018

1 reference

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

21 January 2018

1 reference

Identification of the familial cylindromatosis tumour-suppressor gene

21 January 2018

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

1 reference

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

21 January 2018

1 reference

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

21 January 2018

1 reference

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

21 January 2018

1 reference

Caspase 8 inhibits programmed necrosis by processing CYLD

21 January 2018

1 reference

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

21 January 2018

1 reference

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

1 reference

Survival function of the FADD-CASPASE-8-cFLIP(L) complex

21 January 2018

1 reference

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

21 January 2018

1 reference

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

21 January 2018

1 reference

Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia

21 January 2018

1 reference

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

21 January 2018

1 reference

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

21 January 2018

1 reference

Rational design of inhibitors that bind to inactive kinase conformations

21 January 2018

1 reference

ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development

21 January 2018

1 reference

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

21 January 2018

1 reference

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

21 January 2018

1 reference

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

21 January 2018

1 reference

Fueling the flames: Mammalian programmed necrosis in inflammatory diseases

21 January 2018

1 reference

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24129419

12 December 2020

inferred from PubMed ID database lookup

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24129419

12 December 2020

inferred from PubMed ID database lookup

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24129419

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NRM3683

1 reference

Dimensions Publication ID

29 August 2017

1008747366

0 references

Fatcat ID

release_a3tpeu7kgrhmpogfvj5w2aqkqu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a3tpeu7kgrhmpogfvj5w2aqkqu

24 November 2022

mapped directly with Wikidata item

1 reference