(Q50968563)

http://europepmc.org/abstract/MED/28562585

26 March 2018

title

Crystal structure of the GLP-1 receptor bound to a peptide agonist. (English)

1 reference

http://europepmc.org/abstract/MED/28562585

26 March 2018

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Ali Jazayeri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Mathieu Rappas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Alastair J H Brown

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

James Kean

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

James C Errey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Cédric Fiez-Vandal

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Stephen P Andrews

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Miles Congreve

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Andrea Bortolato

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jonathan S Mason

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Asma H Baig

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Iryna Teobald

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Andrew S Doré

14

1 reference

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12 June 2020

Malcolm Weir

15

1 reference

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12 June 2020

Robert M Cooke

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Fiona H Marshall

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

English

0 references

publication date

31 May 2017

1 reference

http://europepmc.org/abstract/MED/28562585

26 March 2018

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

546

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

7657

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

254-258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28562585%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature22800

12 June 2020

exact match

0 references

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Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

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Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

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Structure of the human glucagon class B G-protein-coupled receptor

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Extra-helical binding site of a glucagon receptor antagonist

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Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs

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Exploration of structure-activity relationships at the two C-terminal residues of potent 11mer Glucagon-Like Peptide-1 receptor agonist peptides via parallel synthesis

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

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Structure of the agonist-bound neurotensin receptor

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Structure of class B GPCR corticotropin-releasing factor receptor 1

21 January 2018

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Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

21 January 2018

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Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)

21 January 2018

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The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling

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The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

21 January 2018

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Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor

21 January 2018

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Characterization of glucagon-like peptide-1 receptor-binding determinants

21 January 2018

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Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation

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Ligand binding pocket formed by evolutionarily conserved residues in the glucagon-like peptide-1 (GLP-1) receptor core domain

21 January 2018

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Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues

21 January 2018

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Molecular basis for negative regulation of the glucagon receptor

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

inferred from DOI database lookup

Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.

1 reference

12 December 2020

Modelling dynamics in protein crystal structures by ensemble refinement

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12 December 2020

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

1 reference

12 December 2020

Small molecule drug discovery at the glucagon-like peptide-1 receptor

1 reference

12 December 2020