(Q38011697)

27 August 2017

8 references

13 March 2019

14 March 2019

24 March 2019

20 June 2019

31 July 2019

19 September 2019

15 December 2019

4 February 2021

Small molecule drug discovery at the glucagon-like peptide-1 receptor (English)

1 reference

biomedical investigative technique

27 August 2017

cell surface receptor

1 reference

31 July 2019

4 references

31 July 2019

19 September 2019

15 December 2019

4 February 2021

1 reference

19 September 2019

1 reference

15 December 2019

1 reference

Francis S Willard

1

1 reference

27 August 2017

Ana B Bueno

series ordinal

2

1 reference

27 August 2017

Kyle W Sloop

series ordinal

3

1 reference

27 August 2017

language of work or name

1 reference

23 February 2012

9 references

Experimental Diabetes Research

27 August 2017

13 March 2019

14 March 2019

24 March 2019

20 June 2019

31 July 2019

19 September 2019

15 December 2019

4 February 2021

9 references

27 August 2017

13 March 2019

14 March 2019

24 March 2019

20 June 2019

31 July 2019

19 September 2019

15 December 2019

4 February 2021

2012

1 reference

27 August 2017

709893

1 reference

Creative Commons Attribution 3.0 Unported

27 August 2017

8 references

13 March 2019

14 March 2019

24 March 2019

20 June 2019

31 July 2019

19 September 2019

15 December 2019

on focus list of Wikimedia project

4 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Structure of the human histamine H1 receptor complex with doxepin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Quantifying ligand bias at seven-transmembrane receptors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Incretin-based therapies for type 2 diabetes mellitus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Drugability of extracellular targets: discovery of small molecule drugs targeting allosteric, functional, and subunit-selective sites on GPCRs and ion channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Structure of a beta1-adrenergic G-protein-coupled receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Small-molecule agonists for the glucagon-like peptide 1 receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

New beta-alanine derivatives are orally available glucagon receptor antagonists

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Molecular properties that influence the oral bioavailability of drug candidates

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Prediction of 'drug-likeness'.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Drug-like properties and the causes of poor solubility and poor permeability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Cloning and functional expression of a human glucagon-like peptide-1 receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Modulation of the glucagon-like peptide-1 receptor signaling by naturally occurring and synthetic flavonoids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Insulin-releasing and metabolic effects of small molecule GLP-1 receptor agonist 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Synthesis and antidiabetic activity of 3,6,7-trisubstituted-2-(1H-imidazol-2-ylsulfanyl)quinoxalines and quinoxalin-2-yl isothioureas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Functional Selectivity and Biased Receptor Signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

A small molecule ligand of the glucagon-like peptide 1 receptor targets its amino-terminal hormone binding domain

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3352573

Structure-Based Discovery of Allosteric Modulators of Two Related Class B G-Protein-Coupled Receptors

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F709893

Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F709893

Cyclobutane derivatives as novel nonpeptidic small molecule agonists of glucagon-like peptide-1 receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22611375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22611375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22611375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2012/709893

1 reference

27 August 2017

1 reference

27 August 2017

PubMed publication ID

22611375

1 reference