(Q50982185)

26 March 2018

title

Distinguishing on-target versus off-target activity in early antibacterial drug discovery using a macromolecular synthesis assay. (English)

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26 March 2018

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Mark L Cunningham

1

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26 March 2018

Bryan P Kwan

2

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26 March 2018

Kirk J Nelson

3

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26 March 2018

Daniel C Bensen

4

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26 March 2018

Karen J Shaw

5

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26 March 2018

publication date

17 May 2013

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26 March 2018

Journal of Biomolecular Screening

published in

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26 March 2018

volume

18

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26 March 2018

issue

9

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26 March 2018

page(s)

1018-1026

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26 March 2018

Antimicrobials: new solutions badly needed

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Mechanism of action and in vitro and in vivo activities of S-6123, a new oxazolidinone compound

21 January 2018

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Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032)

21 January 2018

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Mechanistic studies and biological activity of bioxalomycin alpha 2, a novel antibiotic produced by Streptomyces viridodiastaticus subsp. "litoralis" LL-31F508.

21 January 2018

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Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

21 January 2018

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Interaction of rifamycin with bacterial RNA polymerase

21 January 2018

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Daptomycin exerts bactericidal activity without lysis of Staphylococcus aureus

21 January 2018

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Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus

21 January 2018

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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

21 January 2018

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Mechanisms of action and resistance of older and newer fluoroquinolones

21 January 2018

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The mechanism of inhibition of topoisomerase IV by quinolone antibacterials

21 January 2018

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Opposing effects of aminocoumarins and fluoroquinolones on the SOS response and adaptability in Staphylococcus aureus

21 January 2018

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DNA gyrase on the bacterial chromosome: possibility of two levels of action

21 January 2018

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Specific stimulation of ribosomal RNA synthesis in E. coli by a protein factor

21 January 2018

1 reference

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Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples

21 January 2018

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Mode of action of fluoroquinolones

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1087057113487208

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26 March 2018

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26 March 2018