(Q51058067)

English

Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.

scientific article published on 3 September 2014

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scholarly article

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture. (English)

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

cryopreservation

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object named as

Ulf Norinder

4

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author name string

Lassina Badolo

1

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Bente Jensen

2

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Carolina Säll

3

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Pekka Kallunki

5

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Dino Montanari

6

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

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publication date

3 September 2014

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

45

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

2

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

177-187

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Coordinate transcriptional regulation of transport and metabolism

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Evaluation of models for predicting drug-drug interactions due to induction

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Membrane transporters in drug development

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Drug metabolism in hepatocyte sandwich cultures of rats and humans

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Inhibition and induction of human cytochrome P450 enzymes: current status

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Nuclear receptors and drug disposition gene regulation

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Induction of phase I, II and III drug metabolism/transport by xenobiotics

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2014.955831

21 January 2018

Identifiers

10.3109/00498254.2014.955831

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25183402

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