(Q51546346)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21860411%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1 (English)

1 reference

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11 February 2020

0 references

2

1 reference

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11 February 2020

Philippe Meyer

13

1 reference

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11 February 2020

author name string

H Gaude

1

1 reference

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11 February 2020

A Delay

3

1 reference

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11 February 2020

A Bres

4

1 reference

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11 February 2020

K Buchet-Poyau

5

1 reference

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11 February 2020

C Caillat

6

1 reference

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11 February 2020

A Vigouroux

7

1 reference

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11 February 2020

C Rogon

8

1 reference

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11 February 2020

A Woods

9

1 reference

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11 February 2020

J-M Vanacker

10

1 reference

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11 February 2020

J Höhfeld

11

1 reference

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11 February 2020

C Perret

12

1 reference

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11 February 2020

M Billaud

14

1 reference

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11 February 2020

C Forcet

15

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11 February 2020

language of work or name

English

0 references

publication date

22 August 2011

1 reference

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11 February 2020

1 reference

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11 February 2020

volume

31

1 reference

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11 February 2020

issue

12

1 reference

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11 February 2020

page(s)

1582-1591

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2011.342

11 February 2020

exact match

0 references

cites work

LKB1-dependent signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Depletion of the co-chaperone CDC-37 reveals two modes of PAR-6 cortical association in C. elegans embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Molecular chaperones and protein kinase quality control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Characterization of an alternative splice variant of LKB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

LKB1; linking cell structure and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Energy-dependent regulation of cell structure by AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

CHIP: a link between the chaperone and proteasome systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

The LKB1 tumor suppressor negatively regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

HSP90 and the chaperoning of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Characterization of celastrol to inhibit hsp90 and cdc37 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342

Hsp90 Recognizes a Common Surface on Client Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.342