(Q51570942)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26743860%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity (English)

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4 March 2020

1

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4 March 2020

author name string

Yi Zhang

2

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4 March 2020

Jose C Huguet-Tapia

3

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4 March 2020

Mishal Mehta

4

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4 March 2020

Evelina Dedic

5

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4 March 2020

Steven D Bruner

6

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4 March 2020

Rosemary Loria

7

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4 March 2020

Yousong Ding

8

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4 March 2020

publication date

4 February 2016

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4 March 2020

published in

Biotechnology Journal

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4 March 2020

volume

11

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4 March 2020

issue

5

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4 March 2020

page(s)

624-632

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Microbial remediation of nitro-aromatic compounds: an overview

4 March 2020

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Indole can act as an extracellular signal to regulate biofilm formation of Escherichia coli and other indole-producing bacteria

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Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma

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A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against Trypanosoma brucei in vitro.

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Electrophilic and free radical nitration of benzene and toluene with various nitrating agents

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Pd-catalyzed conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics

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From azides to nitro compounds in a few seconds using HOF.CH3CN.

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Metalloenzymes: Natural product nitrosation

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Reconstitution and characterization of aminopyrrolnitrin oxygenase, a Rieske N-oxygenase that catalyzes unusual arylamine oxidation

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Thaxtomin biosynthesis: the path to plant pathogenicity in the genus Streptomyces.

21 January 2018

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Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

21 January 2018

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Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE.

21 January 2018

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Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE

21 January 2018

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Cytochrome P450 monooxygenases: an update on perspectives for synthetic application.

21 January 2018

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A novel class of self-sufficient cytochrome P450 monooxygenases in prokaryotes.

21 January 2018

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Expanding P450 catalytic reaction space through evolution and engineering

21 January 2018

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The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development.

21 January 2018

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Engineering and application of P450 monooxygenases in pharmaceutical and metabolite synthesis

21 January 2018

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A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center

21 January 2018

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DomCut: prediction of inter-domain linker regions in amino acid sequences

21 January 2018

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Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain

21 January 2018

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Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme.

21 January 2018

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Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity

21 January 2018

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Data-mining for sulfur and fluorine: an evaluation of pharmaceuticals to reveal opportunities for drug design and discovery

21 January 2018

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Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.

21 January 2018

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Engineering human cytochrome P450 enzymes into catalytically self-sufficient chimeras using molecular Lego.

21 January 2018

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Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp. NCIMB 9784.

21 January 2018

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LICRED: a versatile drop-in vector for rapid generation of redox-self-sufficient cytochrome P450s

21 January 2018

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Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes

21 January 2018

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Structure of a cytochrome P450-redox partner electron-transfer complex

21 January 2018

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21 January 2018

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Electron donation to an archaeal cytochrome P450 is enhanced by PCNA-mediated selective complex formation with foreign redox proteins.

21 January 2018

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Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.

21 January 2018

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Controlling substrate specificity and product regio- and stereo-selectivities of P450 enzymes without mutagenesis.

21 January 2018

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The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae

21 January 2018

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Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae

21 January 2018

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Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase

21 January 2018

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Directing Group-Controlled Regioselectivity in an Enzymatic C–H Bond Oxygenation

21 January 2018

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21 January 2018

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A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds

21 January 2018

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Enzymatic nitration of phytophenolics: evidence for peroxynitrite-independent nitration of plant secondary metabolites

21 January 2018

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Formation of reactive nitrogen species at biologic heme centers: a potential mechanism of nitric oxide-dependent toxicity

21 January 2018

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Engineering substrate recognition in catalysis by cytochrome P450cam

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIOT.201500416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26743860%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference