(Q51584140)

7 April 2018

title

Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP. (English)

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7 April 2018

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5

Robert M Tanguay

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7 April 2018

author name string

Alex Daviau

1

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7 April 2018

Roxanne Proulx

2

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7 April 2018

Karine Robitaille

3

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7 April 2018

Marco Di Fruscio

4

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7 April 2018

Jacques Landry

6

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7 April 2018

Cam Patterson

7

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7 April 2018

Yves Durocher

8

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7 April 2018

Richard Blouin

9

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7 April 2018

language of work or name

English

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publication date

24 August 2006

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7 April 2018

Journal of Biological Chemistry

published in

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7 April 2018

volume

281

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7 April 2018

page(s)

31467-31477

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7 April 2018

issue

42

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7 April 2018

Mixed-lineage kinase control of JNK and p38 MAPK pathways

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MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

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Molecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brain

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Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipid

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The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

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Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1

21 January 2018

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Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2

21 January 2018

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The mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrate

21 January 2018

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The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

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The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

21 January 2018

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Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

21 January 2018

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MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase

21 January 2018

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Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components

21 January 2018

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Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation

21 January 2018

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Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurin

21 January 2018

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Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development

21 January 2018

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"The stress of dying": the role of heat shock proteins in the regulation of apoptosis

21 January 2018

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Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology

21 January 2018

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Heat-shock proteins as regulators of apoptosis

21 January 2018

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Localization of the mixed-lineage kinase DLK/MUK/ZPK to the Golgi apparatus in NIH 3T3 cells

21 January 2018

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

1 reference

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Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70

21 January 2018

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Degradation of CFTR by the ubiquitin-proteasome pathway

21 January 2018

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Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

21 January 2018

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Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding

21 January 2018

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Rho-modifying C3-like ADP-ribosyltransferases

21 January 2018

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Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

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Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 January 2018

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Roles of molecular chaperones in protein degradation

21 January 2018

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From the cradle to the grave: molecular chaperones that may choose between folding and degradation

21 January 2018

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

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CHIP: a link between the chaperone and proteasome systems

21 January 2018

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Dual leucine zipper-bearing kinase (DLK) activates p46SAPK and p38mapk but not ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Hsp70 chaperones: cellular functions and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

The Hsp70 and Hsp60 chaperone machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Negative regulation of the Apaf-1 apoptosome by Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

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Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase

21 January 2018

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Roles of MAPKKK ASK1 in stress-induced cell death.

21 January 2018

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Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1.

21 January 2018

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BAG-1--a nucleotide exchange factor of Hsc70 with multiple cellular functions

21 January 2018

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Mechanisms for regulation of Hsp70 function by Hsp40

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M607612200

Hop: more than an Hsp70/Hsp90 adaptor protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M607612200

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

21 January 2018

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

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HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607612200

21 January 2018

Identifiers

DOI

10.1074/JBC.M607612200

1 reference

7 April 2018

PubMed ID

16931512

1 reference

7 April 2018