(Q51750017)

English

Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells.

scientific article published on 21 February 2014

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. (English)

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

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Gyun Min Lee

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

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Jong Kwang Hong

1

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

Sang Min Lee

2

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

Kyung-Yong Kim

3

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

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publication date

21 February 2014

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

Applied Microbiology and Biotechnology

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

98

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

12

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

5417-5425

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

Effects of charge on antibody tissue distribution and pharmacokinetics.

1 reference

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Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts

1 reference

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21 January 2018

Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells

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Increased productivity of recombinant tissular plasminogen activator (t-PA) by butyrate and shift of temperature: a cell cycle phases analysis

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Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells.

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Optimal and consistent protein glycosylation in mammalian cell culture

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Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture.

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Glycosylation as a strategy to improve antibody-based therapeutics

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Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility

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21 January 2018

Characterization of the basic charge variants of a human IgG1: effect of copper concentration in cell culture media

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21 January 2018

Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats

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21 January 2018

Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3.

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Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells.

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21 January 2018

Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate

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21 January 2018

Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding

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21 January 2018

The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin

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21 January 2018

Heterogeneity of monoclonal antibodies

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21 January 2018

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

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21 January 2018

Butyrate increases production of human chimeric IgG in CHO-K1 cells whilst maintaining function and glycoform profile

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21 January 2018

Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn

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21 January 2018

Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions.

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21 January 2018

Aberrant metabolic sialylation of recombinant proteins expressed in Chinese hamster ovary cells in high productivity cultures

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21 January 2018

On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.

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21 January 2018

Enhanced human thrombopoietin production by sodium butyrate addition to serum-free suspension culture of bcl-2-overexpressing CHO cells

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21 January 2018

Effect of sodium butyrate on the production, heterogeneity and biological activity of human thrombopoietin by recombinant Chinese hamster ovary cells

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21 January 2018

Butyrate-induced transcriptional changes in human colonic mucosa

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21 January 2018

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods

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21 January 2018

Effect of simultaneous application of stressful culture conditions on specific productivity and heterogeneity of erythropoietin in Chinese hamster ovary cells.

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21 January 2018

Isolation and characterization of therapeutic antibody charge variants using cation exchange displacement chromatography

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21 January 2018

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

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21 January 2018

Synthesis of Excess Light Chains of Gamma Globulin by Rabbit Lymph Node Cells

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21 January 2018

Identifiers

10.1007/S00253-014-5596-8

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/24557571

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