(Q51755936)

11 April 2018

title

Total synthesis of (18S)- and (18R)-homolargazole by rhodium-catalyzed hydrocarboxylation. (English)

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11 April 2018

author

Manfred Jung

5

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11 April 2018

Bernhard Breit

6

object named as

Bernhard Breit

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11 April 2018

Karin Schmidtkunz

4

object named as

Karin Schmidtkunz

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11 April 2018

author name string

Christoph Schotes

1

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11 April 2018

Dmytro Ostrovskyi

2

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Johanna Senger

3

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language of work or name

English

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publication date

29 January 2014

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11 April 2018

Chemistry—A European Journal

published in

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11 April 2018

volume

20

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11 April 2018

issue

8

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11 April 2018

page(s)

2164-2168

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11 April 2018

Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp.

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In Vitro and In Vivo Osteogenic Activity of Largazole.

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Structural Basis of the Antiproliferative Activity of Largazole, a Depsipeptide Inhibitor of the Histone Deacetylases

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Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold

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Chemical phylogenetics of histone deacetylases

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The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

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The role of histone deacetylase inhibitors in the treatment of patients with cutaneous T-cell lymphoma

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Macrocyclic histone deacetylase inhibitors

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Total synthesis and molecular target of largazole, a histone deacetylase inhibitor

21 January 2018

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Total syntheses of the histone deacetylase inhibitors largazole and 2-epi-largazole: application of N-heterocyclic carbene mediated acylations in complex molecule synthesis

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21 January 2018

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Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells

21 January 2018

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Largazole and analogues with modified metal-binding motifs targeting histone deacetylases: synthesis and biological evaluation

21 January 2018

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A concise total synthesis of largazole, solution structure, and some preliminary structure activity relationships

21 January 2018

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Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole

21 January 2018

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Synthesis and biological evaluation of c7-demethyl largazole analogues

21 January 2018

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Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor

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Enantioselective total synthesis of (+)-largazole, a potent inhibitor of histone deacetylase

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Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7- modified analogues

21 January 2018

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Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability.

21 January 2018

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Synthesis and activity of largazole analogues with linker and macrocycle modification

21 January 2018

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Evaluation of the pharmacodynamic effects of MGCD0103 from preclinical models to human using a novel HDAC enzyme assay

21 January 2018

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Nitro-Substituted Hoveyda−Grubbs Ruthenium Carbenes: Enhancement of Catalyst Activity through Electronic Activation

21 January 2018

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https://api.crossref.org/works/10.1002%2FCHEM.201303300

21 January 2018

Identifiers

DOI

10.1002/CHEM.201303300

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11 April 2018

PubMed ID

24478039

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11 April 2018