(Q51790493)

English

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.

scientific article published on 2 November 2017

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice. (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Human Induced Pluripotent Stem Cells

1 reference

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author name string

Xiao Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Avanthi Raghavan

2

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Derek T Peters

3

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Evanthia E Pashos

4

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Daniel J Rader

5

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Kiran Musunuru

6

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

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publication date

2 November 2017

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Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Arteriosclerosis, Thrombosis, and Vascular Biology

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Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

38

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Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

1

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

76-82

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo-Brief Report

1 reference

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25 August 2018

A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

1 reference

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Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

1 reference

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25 August 2018

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Pluripotent stem cell-derived hepatocyte-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Biological, clinical and population relevance of 95 loci for blood lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

General review on in vitro hepatocyte models and their applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Mapping the genetic architecture of gene expression in human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Genomewide association analysis of coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Size matters: use of YACs, BACs and PACs in transgenic animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Adenovirus-mediated gene transfer into human hepatocytes: analysis of the biochemical functionality of transduced cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746470

25 August 2018

Identifiers

10.1161/ATVBAHA.117.310103

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/29097363

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