(Q51828635)

13 April 2018

title

Apoptotic and mitogenic stimuli inactivate Rb by differential utilization of p38 and cyclin-dependent kinases. (English)

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13 April 2018

1 reference

Niharika Nath

1

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13 April 2018

Sheng Wang

2

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13 April 2018

Vicki Betts

3

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13 April 2018

Erik Knudsen

4

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13 April 2018

Srikumar Chellappan

5

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13 April 2018

language of work or name

English

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publication date

1 September 2003

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13 April 2018

published in

Oncogene

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13 April 2018

volume

22

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13 April 2018

issue

38

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13 April 2018

page(s)

5986-5994

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13 April 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206843

exact match

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cites work

Transcriptional control by E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

The cellular effects of E2F overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The E2F transcription factor is a cellular target for the RB protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Rb function in cell-cycle regulation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Regulation of cell proliferation by the E2F transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The transcription factor E2F1 modulates apoptosis of neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Rb interacts with histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The Rb/E2F pathway and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F-1 induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The ins and outs of RB: coupling gene expression to the cell cycle clock

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The caspase-RB connection in cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

RB kinases and RB-binding proteins: new points of view

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Retinoblastoma protein in growth suppression and death protection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206843

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206843

1 reference

13 April 2018

1 reference

13 April 2018