(Q51864092)

14 April 2018

title

Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury. (English)

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14 April 2018

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9

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14 April 2018

Pierre Gressens

10

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14 April 2018

Xiaoyang Wang

Xiaoyang Wang

5

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Ylva Carlsson

1

Ylva Carlsson

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14 April 2018

Etienne Jacotot

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Etienne Jacotot

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14 April 2018

Leslie Schwendimann

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Leslie Schwendimann

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14 April 2018

Regina T Vontell

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Regina Vontell

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14 April 2018

Veena Supramaniam

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Veena Supramaniam

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14 April 2018

Sophie Lebon

6

Sophie Lebon

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14 April 2018

author name string

Catherine I Rousset

4

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14 April 2018

Christiane Charriaut-Marlangue

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14 April 2018

publication date

14 June 2011

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14 April 2018

published in

Annals of Neurology

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14 April 2018

volume

70

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issue

5

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14 April 2018

page(s)

781-789

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14 April 2018

Perinatal brain injury in the preterm and term newborn

cites work

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Moderate hypothermia to treat perinatal asphyxial encephalopathy.

21 January 2018

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Neuroprotection in the newborn infant

21 January 2018

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Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain

21 January 2018

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Molecular mechanisms involved in injury to the preterm brain

21 January 2018

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Apoptotic mechanisms in the immature brain: involvement of mitochondria

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Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury

21 January 2018

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Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury.

21 January 2018

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21 January 2018

Caspases: enemies within

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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

21 January 2018

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Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak.

21 January 2018

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Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons

21 January 2018

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Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?

21 January 2018

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The role of caspase-2 in stress-induced apoptosis

21 January 2018

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The unpredictable caspase-2: what can it do?

21 January 2018

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

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Characterization of cytoplasmic caspase-2 activation by induced proximity.

21 January 2018

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Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

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The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats

21 January 2018

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Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice.

21 January 2018

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Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

21 January 2018

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The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.

21 January 2018

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Neurodegeneration in the thalamus following neonatal hypoxia-ischemia is programmed cell death

21 January 2018

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Excitotoxicity in perinatal brain injury

21 January 2018

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Enhancing and confirming the specificity of RNAi experiments

21 January 2018

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Upstream control of apoptosis by caspase-2 in serum-deprived primary neurons.

21 January 2018

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Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation

21 January 2018

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Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

21 January 2018

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Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury

21 January 2018

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Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways.

21 January 2018

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Caspase inhibition after neonatal ischemia in the rat brain

21 January 2018

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Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

21 January 2018

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Postischemic treatment of neonatal cerebral ischemia should target autophagy.

21 January 2018

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A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.

21 January 2018

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Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: implications for synaptic plasticity and excitotoxic neuronal death

21 January 2018

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Non-apoptotic functions of caspase-3 in nervous tissue

21 January 2018

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Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

21 January 2018

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.22431

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14 April 2018

PubMed ID

21674587

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14 April 2018