(Q51945372)

English

Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor.

scientific article published on 4 December 2008

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Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

author name string

Eyal J Scheinman

1

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

Orly Avni

2

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

language of work or name

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publication date

4 December 2008

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

284

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

5

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

3037-3048

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

Regulation of Th2 differentiation and Il4 locus accessibility.

1 reference

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21 January 2018

T helper cell differentiation: regulation by cis elements and epigenetics

1 reference

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21 January 2018

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment

1 reference

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21 January 2018

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

1 reference

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21 January 2018

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus

1 reference

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21 January 2018

Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Transcription factor GATA-3 is required for development of the T-cell lineage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Essential role of Gata transcription factors in sympathetic neuron development

1 reference

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21 January 2018

Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Hearing loss following Gata3 haploinsufficiency is caused by cochlear disorder

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3: an unexpected regulator of cell lineage determination in skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Dosage-dependent rescue of definitive nephrogenesis by a distant Gata3 enhancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA3 haplo-insufficiency causes human HDR syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Enforced expression of GATA-3 severely reduces human thymic cellularity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Mutation of GATA3 in human breast tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Protein kinase A-dependent synergism between GATA factors and the nuclear receptor, liver receptor homolog-1, regulates human aromatase (CYP19) PII promoter activity in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Aberrant gata-3 expression in human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Down-regulation of GATA-3 expression during human papillomavirus-mediated immortalization and cervical carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Gene silencing quantitatively controls the function of a developmental trans-activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

ROG, repressor of GATA, regulates the expression of cytokine genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Friend of GATA is expressed in naive Th cells and functions as a repressor of GATA-3-mediated Th2 cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Stat6 regulation of in vivo IL-4 responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch directly regulates Gata3 expression during T helper 2 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

T-cell expression of the human GATA-3 gene is regulated by a non-lineage-specific silencer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Crucial role of MLL for the maintenance of memory T helper type 2 cell responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch signaling augments T cell responsiveness by enhancing CD25 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Recognition sequence of a highly conserved DNA binding protein RBP-J kappa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Jaks and STATs: biological implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch1 co-localizes with CD4 on activated T cells and Notch signaling is required for IL-10 production.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Variations on the Notch pathway in neural development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Notch signalling during peripheral T-cell activation and differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Interaction of the nuclear protein CBF1 with the kappaB site of the IL-6 gene promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Differential T cell costimulatory requirements in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Demethylation of a specific hypersensitive site in the Th2 locus control region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Controlling NF-kappaB activation in T cells by costimulatory receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Interleukin-4 receptor signaling pathways in asthma pathogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

The IL-4 receptor: signaling mechanisms and biologic functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

The functional consequences of alternative promoter use in mammalian genomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Regulation of GATA gene expression during vertebrate development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Structure and expression of the human GATA3 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Temporal and Spatial Control of Murine GATA-3 Transcription by Promoter-Proximal Regulatory Elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807302200

21 January 2018

Identifiers

10.1074/JBC.M807302200

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 April 2018

http://europepmc.org/abstract/MED/19056736

ResearchGate publication ID

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