(Q52309219)

29 April 2018

title

Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. (English)

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29 April 2018

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8

Shauna Hill

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29 April 2018

15

Holly Van Remmen

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29 April 2018

12

Jonathan D Wren

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29 April 2018

Arlan G. Richardson

14

object named as

Arlan Richardson

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29 April 2018

Carlo Viscomi

13

object named as

Carlo Viscomi

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29 April 2018

author name string

Sathyaseelan S Deepa

1

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29 April 2018

Gavin Pharaoh

2

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29 April 2018

Michael Kinter

3

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29 April 2018

Vivian Diaz

4

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29 April 2018

Wilson C Fok

5

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29 April 2018

Kaitlyn Riddle

6

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29 April 2018

Daniel Pulliam

7

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29 April 2018

Kathleen E Fischer

9

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29 April 2018

Vanessa Soto

10

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29 April 2018

Constantin Georgescu

11

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29 April 2018

publication date

25 April 2018

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29 April 2018

published in

Aging Cell

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29 April 2018

page(s)

e12769

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29 April 2018

A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated

cites work

1 reference

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Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts

25 August 2018

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Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life

25 August 2018

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Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis

25 August 2018

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Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction.

25 August 2018

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Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses

25 August 2018

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25 August 2018

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The paradox of mitochondrial dysfunction and extended longevity

25 August 2018

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The influence of Shc proteins on life span in mice.

25 August 2018

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Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice

25 August 2018

1 reference

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Rapamycin extends life and health in C57BL/6 mice

25 August 2018

1 reference

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A quantitative proteomic profile of the Nrf2-mediated antioxidant response of macrophages to oxidized LDL determined by multiplexed selected reaction monitoring

25 August 2018

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Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells.

25 August 2018

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Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?

25 August 2018

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A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice

25 August 2018

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Quality control of mitochondrial proteostasis

25 August 2018

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Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain

25 August 2018

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Lifespan extension in genetically modified mice

25 August 2018

1 reference

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Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

25 August 2018

1 reference

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Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy

25 August 2018

1 reference

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Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

25 August 2018

1 reference

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Brain IRS2 signaling coordinates life span and nutrient homeostasis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Mitochondrial point mutations do not limit the natural lifespan of mice.

25 August 2018

1 reference

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Novel method for high-throughput phenotyping of sleep in mice.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Post-transcriptional silencing and functional characterization of the Drosophila melanogaster homolog of human Surf1.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Genetic mouse models of extended lifespan

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Rates of behavior and aging specified by mitochondrial function during development

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Mitochondrial threshold effects.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

The p66shc adaptor protein controls oxidative stress response and life span in mammals

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

The kinetic basis of threshold effects observed in mitochondrial diseases: a systemic approach

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

The biologic clock: the mitochondria?

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6052393

Background pathology in BDF1 mice allowed to live out their life-span

25 August 2018

1 reference

12 December 2020

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

1 reference

12 December 2020

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

1 reference

12 December 2020

Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice

1 reference

12 December 2020

Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis"

1 reference

12 December 2020

Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity

1 reference

12 December 2020

Identifiers

DOI

10.1111/ACEL.12769

1 reference

29 April 2018

release_h5axiiy2xjetjmxpvh5n6ec6ke

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h5axiiy2xjetjmxpvh5n6ec6ke

24 November 2022

mapped directly with Wikidata item

0 references

1 reference

29 April 2018