(Q52321029)

15 June 2018

title

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal. (English)

1 reference

15 June 2018

author

José I López

6

1 reference

http://europepmc.org/abstract/MED/29656895

29 April 2018

Aengus Stewart

Aengus Stewart

35

0 references

Stuart Horswell

Stuart Horswell

10

0 references

Hang Xu

Hang Xu

2

0 references

Lavinia Spain

Lavinia Spain

26

0 references

Charles Swanton

Charles Swanton

49

0 references

Samra Turajlic

1

Samra Turajlic

1 reference

15 June 2018

Tim Chambers

5

Tim Chambers

1 reference

15 June 2018

David Kerr

7

David Nicol

1 reference

15 June 2018

Mark Stares

11

Mark Stares

1 reference

15 June 2018

Steve Hazell

16

Steve Hazell

1 reference

15 June 2018

Ashish Chandra

15

Ashish Chandra

1 reference

15 June 2018

Claudia Eichler-Jonsson

17

Claudia Eichler-Jonsson

1 reference

15 June 2018

Faiz Jabbar

25

Faiz Jabbar

1 reference

15 June 2018

Aspasia Soultati

18

Aspasia Soultati

1 reference

15 June 2018

Simon Chowdhury

19

Simon Chowdhury

1 reference

15 June 2018

Sarah M Rudman

20

Sarah Rudman

1 reference

15 June 2018

Joanna Lynch

21

Joanna Lynch

1 reference

15 June 2018

Archana Fernando

22

Archana Fernando

1 reference

15 June 2018

Gordon Stamp

23

Gordon Stamp

1 reference

15 June 2018

Sharanpreet Lall

27

Sharanpreet Lall

1 reference

15 June 2018

Lisa Pickering

31

Lisa Pickering

1 reference

15 June 2018

Mariam Jamal-Hanjani

13

Mariam Jamal-Hanjani

1 reference

15 June 2018

TRACERx Renal Consortium

51

TRACERx Renal Consortium

1 reference

15 June 2018

Mary Falzon

29

Mary Falzon

1 reference

15 June 2018

Kevin Litchfield

3

Kevin Litchfield

1 reference

15 June 2018

James J Hsieh

39

James J Hsieh

1 reference

15 June 2018

author name string

Andrew Rowan

4

1 reference

15 June 2018

Tim O'Brien

8

1 reference

15 June 2018

James Larkin

9

1 reference

15 June 2018

Lewis Au

12

1 reference

15 June 2018

Ben Challacombe

14

1 reference

15 June 2018

Emma Nye

24

1 reference

15 June 2018

Rosa Guarch

28

1 reference

15 June 2018

Ian Proctor

30

1 reference

15 June 2018

Martin Gore

32

1 reference

15 June 2018

Thomas B K Watkins

33

1 reference

15 June 2018

Sophia Ward

34

1 reference

15 June 2018

Renzo DiNatale

36

1 reference

15 June 2018

Maria F Becerra

37

1 reference

15 June 2018

Ed Reznik

38

1 reference

15 June 2018

Todd A Richmond

40

1 reference

15 June 2018

George F Mayhew

41

1 reference

15 June 2018

Samantha M Hill

42

1 reference

15 June 2018

Catherine D McNally

43

1 reference

15 June 2018

Carol Jones

44

1 reference

15 June 2018

Heidi Rosenbaum

45

1 reference

15 June 2018

Stacey Stanislaw

46

1 reference

15 June 2018

Daniel L Burgess

47

1 reference

15 June 2018

Nelson R Alexander

48

1 reference

15 June 2018

PEACE

50

1 reference

15 June 2018

language of work or name

English

0 references

publication date

12 April 2018

1 reference

15 June 2018

published in

Cell

1 reference

15 June 2018

volume

173

1 reference

15 June 2018

issue

3

1 reference

15 June 2018

page(s)

581-594.e12

1 reference

15 June 2018

Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

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1 reference

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Genomic Evolution of Breast Cancer Metastasis and Relapse

16 June 2018

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Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma

16 June 2018

1 reference

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

16 June 2018

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Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.

16 June 2018

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Indel variant analysis of short-read sequencing data with Scalpel.

16 June 2018

1 reference

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A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

16 June 2018

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Punctuated copy number evolution and clonal stasis in triple-negative breast cancer

16 June 2018

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Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.

16 June 2018

1 reference

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CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

TRONCO: an R package for the inference of cancer progression models from heterogeneous genomic data.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Early and multiple origins of metastatic lineages within primary tumors

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Management of inferior vena cava tumor thrombus in locally advanced renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Clear Cell Renal Cell Carcinoma Subtypes Identified by BAP1 and PBRM1 Expression.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Short- and long-term effects of chromosome mis-segregation and aneuploidy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The evolutionary history of lethal metastatic prostate cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Local treatments for metastases of renal cell carcinoma: a systematic review.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Comparative genomic analysis of primary and synchronous metastatic colorectal cancers

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Mechanisms governing metastatic dormancy and reactivation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

A mill based instrument and software system for dissecting slide-mounted tissue that provides digital guidance and documentation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Tracking the clonal origin of lethal prostate cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Impact of bone and liver metastases on patients with renal cell carcinoma treated with targeted therapy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Integrated molecular analysis of clear-cell renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The life history of 21 breast cancers

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Absolute quantification of somatic DNA alterations in human cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The perioperative management of an inferior vena caval tumor thrombus in patients with renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Allele-specific copy number analysis of tumors

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Genome remodelling in a basal-like breast cancer metastasis and xenograft

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

p16 Modulates VEGF expression via its interaction with HIF-1alpha in breast cancer cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

BEDTools: a flexible suite of utilities for comparing genomic features

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Use of systemic therapy and factors affecting survival for patients undergoing cytoreductive nephrectomy.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

VarScan: variant detection in massively parallel sequencing of individual and pooled samples

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Fast and accurate short read alignment with Burrows-Wheeler transform

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Surgical management of large renal tumors

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

On punctuated equilibria.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The Role of Lymph Node Dissection in the Management of Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Punctuated evolution of canonical genomic aberrations in uveal melanoma.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Integrative clinical genomics of metastatic cancer.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Renal Cell Carcinoma with Isolated Lymph Node Involvement: Long-term Natural History and Predictors of Oncologic Outcomes Following Surgical Resection.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

The Role of Cytoreductive Nephrectomy: European Association of Urology Recommendations in 2016.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Variation in genomic landscape of clear cell renal cell carcinoma across Europe.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Natural history of untreated renal cell carcinoma with venous tumor thrombus

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Distribution of metastatic sites in renal cell carcinoma: a population-based analysis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Chromosome 9p deletions identify an aggressive phenotype of clear cell renal cell carcinoma

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

Oligometastases revisited

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938365

10.1016/J.CELL.2018.03.057

30 November 2018

Identifiers

DOI

1 reference

15 June 2018

PMCID

5938365

1 reference

15 June 2018

PubMed ID

29656895

1 reference

15 June 2018