(Q52321041)

16 June 2018

title

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. (English)

1 reference

16 June 2018

author

Thomas Mitchell

1

1 reference

http://europepmc.org/abstract/MED/29656891

29 April 2018

José I López

16

1 reference

http://europepmc.org/abstract/MED/29656891

29 April 2018

Aengus Stewart

Aengus Stewart

36

0 references

Stuart Horswell

Stuart Horswell

32

0 references

Grant D. Stewart

Grant D Stewart

13

0 references

Andy G. Lynch

Andy G Lynch

44

0 references

David C. Wedge

David C Wedge

31

0 references

P. Andrew Futreal

42

P Andrew Futreal

1 reference

16 June 2018

Lavinia Spain

26

0 references

Charles Swanton

Charles Swanton

46

0 references

Hang Xu

Hang Xu

35

0 references

Nicholas McGranahan

39

Nicholas McGranahan

1 reference

16 June 2018

45

Zoltan Szallasi

1 reference

16 June 2018

12

Keiran Raine

1 reference

16 June 2018

29

Jon Teague

1 reference

16 June 2018

40

Istvan Csabai

1 reference

16 June 2018

Peter J Campbell

47

Peter J Campbell

1 reference

16 June 2018

Samra Turajlic

2

Samra Turajlic

1 reference

16 June 2018

Tim Chambers

33

Tim Chambers

1 reference

16 June 2018

David Kerr

4

David Nicol

1 reference

16 June 2018

Mark Stares

28

Mark Stares

1 reference

16 June 2018

Steve Hazell

17

Steve Hazell

1 reference

16 June 2018

Ashish Chandra

18

Ashish Chandra

1 reference

16 June 2018

Aspasia Soultati

21

Aspasia Soultati

1 reference

16 June 2018

Simon Chowdhury

19

Simon Chowdhury

1 reference

16 June 2018

Sarah M Rudman

20

Sarah Rudman

1 reference

16 June 2018

Joanna Lynch

27

Joanna Lynch

1 reference

16 June 2018

Archana Fernando

15

Archana Fernando

1 reference

16 June 2018

Gordon Stamp

22

Gordon Stamp

1 reference

16 June 2018

Nicos Fotiadis

23

Nicos Fotiadis

1 reference

16 June 2018

Lisa Pickering

24

Lisa Pickering

1 reference

16 June 2018

TRACERx Renal Consortium

48

TRACERx Renal Consortium

1 reference

16 June 2018

Patrick S. Tarpey

8

Patrick Tarpey

1 reference

16 June 2018

Kevin Litchfield

34

Kevin Litchfield

1 reference

16 June 2018

author name string

Andrew Rowan

3

1 reference

16 June 2018

James H R Farmery

5

1 reference

16 June 2018

Tim O'Brien

6

1 reference

16 June 2018

Inigo Martincorena

7

1 reference

16 June 2018

Nicos Angelopoulos

9

1 reference

16 June 2018

Lucy R Yates

10

1 reference

16 June 2018

Adam P Butler

11

1 reference

16 June 2018

Ben Challacombe

14

1 reference

16 June 2018

Lewis Au

25

1 reference

16 June 2018

Francesco Maura

30

1 reference

16 June 2018

Reza Elaidi

37

1 reference

16 June 2018

Stéphane Oudard

38

1 reference

16 June 2018

Martin Gore

41

1 reference

16 June 2018

James Larkin

43

1 reference

16 June 2018

language of work or name

English

0 references

publication date

12 April 2018

1 reference

16 June 2018

published in

Cell

1 reference

16 June 2018

volume

173

1 reference

16 June 2018

issue

3

1 reference

16 June 2018

page(s)

611-623.e17

1 reference

16 June 2018

describes a project that uses

edgeR

R package edgeR

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours

16 June 2018

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Landscape of somatic mutations in 560 breast cancer whole-genome sequences

16 June 2018

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Von Hippel-Lindau Disease: Genetics and Role of Genetic Counseling in a Multiple Neoplasia Syndrome.

16 June 2018

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MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

16 June 2018

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Chromothripsis and Kataegis Induced by Telomere Crisis

16 June 2018

1 reference

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Clock-like mutational processes in human somatic cells

16 June 2018

1 reference

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Gene essentiality and synthetic lethality in haploid human cells

16 June 2018

1 reference

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Identification and characterization of essential genes in the human genome.

16 June 2018

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16 June 2018

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Chromothripsis from DNA damage in micronuclei.

16 June 2018

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Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

16 June 2018

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A clearer view of the molecular complexity of clear cell renal cell carcinoma.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

16 June 2018

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

16 June 2018

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The somatic genomic landscape of chromophobe renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

The elusive evidence for chromothripsis

16 June 2018

1 reference

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Genome recognition by MYC.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Signatures of mutational processes in human cancer

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Integrated molecular analysis of clear-cell renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Comprehensive molecular characterization of clear cell renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Mutational heterogeneity in cancer and the search for new cancer-associated genes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Criteria for inference of chromothripsis in cancer genomes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Highly recurrent TERT promoter mutations in human melanoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

TERT promoter mutations in familial and sporadic melanoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Cancer vulnerabilities unveiled by genomic loss

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

The origin and evolution of mutations in acute myeloid leukemia

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

The life history of 21 breast cancers

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Estimation of rearrangement phylogeny for cancer genomes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Temporal dissection of tumorigenesis in primary cancers

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

The landscape of somatic copy-number alteration across human cancers

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Genotype-phenotype correlations in von Hippel-Lindau disease.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Identification of Mad as a repressor of the human telomerase (hTERT) gene

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Direct activation of TERT transcription by c-MYC.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Mutation and cancer: statistical study of retinoblastoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Universal Patterns of Selection in Cancer and Somatic Tissues

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

TRACERx Renal: tracking renal cancer evolution through therapy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Variation in genomic landscape of clear cell renal cell carcinoma across Europe.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927631

Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma

13 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29656891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specific chromosome aberration in human renal cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29656891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

cgpPindel: Identifying Somatically Acquired Insertion and Deletion Events from Paired End Sequencing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29656891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2018.02.020

1 reference

16 June 2018

PMCID

5927631

1 reference

16 June 2018

PubMed ID

29656891

1 reference

16 June 2018