(Q35752935)

10 August 2017

title

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin (English)

1 reference

10 August 2017

13

Sara Widaa

0 references

Anthony Fullam

Anthony Fullam

8

0 references

Amit Roshan

Amit Roshan

2

0 references

Moritz Gerstung

Moritz Gerstung

3

0 references

Philip H. Jones

Philip H Jones

15

0 references

David C. Wedge

David C Wedge

7

0 references

Peter Van Loo

Peter Van Loo

5

0 references

Andrew Menzies

12

Andrew Menzies

1 reference

10 August 2017

14

Michael R Stratton

1 reference

10 August 2017

Iñigo Martincorena

1

1 reference

10 August 2017

Peter Ellis

4

1 reference

10 August 2017

Stuart McLaren

6

1 reference

10 August 2017

Ludmil B Alexandrov

9

1 reference

10 August 2017

Jose M Tubio

10

1 reference

10 August 2017

Lucy Stebbings

11

1 reference

10 August 2017

Peter J Campbell

16

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 May 2015

1 reference

10 August 2017

1 reference

10 August 2017

volume

348

1 reference

10 August 2017

issue

6237

1 reference

10 August 2017

page(s)

880-886

1 reference

Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

2 October 2017

UV signature mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Mutational landscape of aggressive cutaneous squamous cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Subclonal variant calling with multiple samples and prior knowledge

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Signatures of mutational processes in human cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Lessons from the cancer genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

2 October 2017

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Non-random mutation: the evolution of targeted hypermutation and hypomutation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Comprehensive genomic characterization of squamous cell lung cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

The origin and evolution of mutations in acute myeloid leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

A landscape of driver mutations in melanoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

The life history of 21 breast cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

A systematic review of worldwide incidence of nonmelanoma skin cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Temporal dissection of tumorigenesis in primary cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

The mutational landscape of head and neck squamous cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Notch Signaling in the Regulation of Stem Cell Self-Renewal and Differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Statistical analysis of pathogenicity of somatic mutations in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Mutations induced by ultraviolet light

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Persistent p53 mutations in single cells from normal human skin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Frequent clones of p53-mutated keratinocytes in normal human skin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Non-melanoma skin cancer and solar keratoses. I. Methods and descriptive results of the South Wales Skin Cancer Study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

The clonal evolution of tumor cell populations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Mutational landscape of basal cell carcinomas by whole-exome sequencing.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

G-to-T transversions and small tandem base deletions are the hallmark of mutations induced by ultraviolet a radiation in mammalian cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4471149

Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C

25 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Fast and accurate short read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Detection of ultra-rare mutations by next-generation sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Cancer evolution is associated with pervasive positive selection on globally expressed genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Mutational heterogeneity in cancer and the search for new cancer-associated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Synonymous and nonsynonymous rate variation in nuclear genes of mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Allele-specific copy number analysis of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Clinical and biological implications of driver mutations in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Genome sequencing of normal cells reveals developmental lineages and mutational processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA6806

The mutation rate and cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25999502

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAA6806

1 reference

release_qqyzb4mefbatvpshfzfjqehabu

10 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qqyzb4mefbatvpshfzfjqehabu

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4471149

1 reference

10 August 2017

1 reference