(Q52329462)

PubMed publication ID

29626215

29 April 2018

http://europepmc.org/abstract/MED/29626215

title

The coming of age of chaperone-mediated autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

author name string

Susmita Kaushik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

publication date

6 April 2018

1 reference

PubMed publication ID

29626215

29 April 2018

http://europepmc.org/abstract/MED/29626215

published in

Nature Reviews Molecular Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

volume

19

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

page(s)

365-381

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

To be or not to be? How selective autophagy and cell death govern cell fate

13 May 2020

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Chaperone-mediated autophagy is required for tumor growth

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7 January 2021

Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation

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7 January 2021

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

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7 January 2021

Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation

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7 January 2021

AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

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7 January 2021

Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

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7 January 2021

Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.

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7 January 2021

Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer

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7 January 2021

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

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7 January 2021

Acetylation of translationally controlled tumor protein promotes its degradation through chaperone-mediated autophagy.

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7 January 2021

K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy.

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7 January 2021

Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth

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7 January 2021

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

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7 January 2021

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

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7 January 2021

Chaperone-assisted selective autophagy is essential for muscle maintenance

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7 January 2021

A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins

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7 January 2021

An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation

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7 January 2021

Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

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7 January 2021

A receptor for the selective uptake and degradation of proteins by lysosomes

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7 January 2021

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

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7 January 2021

Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export

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7 January 2021

Regulation of lamp2a levels in the lysosomal membrane

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7 January 2021

Structure of transmembrane domain of lysosome-associated membrane protein type 2a (LAMP-2A) reveals key features for substrate specificity in chaperone-mediated autophagy.

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7 January 2021

Activation of chaperone-mediated autophagy during oxidative stress

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7 January 2021

Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression

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7 January 2021

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

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7 January 2021

A gene network regulating lysosomal biogenesis and function

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7 January 2021

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy

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7 January 2021

Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx

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7 January 2021

Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor

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7 January 2021

Inhibitory effect of dietary lipids on chaperone-mediated autophagy

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7 January 2021

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7 January 2021

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

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7 January 2021

Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.

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7 January 2021

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

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7 January 2021

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

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7 January 2021

Hypoxic stress activates chaperone-mediated autophagy and modulates neuronal cell survival.

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7 January 2021

Ketone bodies stimulate chaperone-mediated autophagy

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7 January 2021

Direct lysosomal uptake of alpha 2-microglobulin contributes to chemically induced nephropathy

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7 January 2021

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

1 reference

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7 January 2021

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Autophagy regulates lipid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Salmonella Co-opts Host Cell Chaperone-mediated Autophagy for Intracellular Growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Dual proteolytic pathways govern glycolysis and immune competence

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

IkappaB is a substrate for a selective pathway of lysosomal proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

A mechanism regulating proteolysis of specific proteins during renal tubular cell growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Disruption of chaperone-mediated autophagy-dependent degradation of MEF2A by oxidative stress-induced lysosome destabilization

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus

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7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Balance between autophagic pathways preserves retinal homeostasis

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy: roles in neuroprotection

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy: roles in disease and aging

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Lysosomal degradation of alpha-synuclein in vivo.

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Regional deficiencies in chaperone-mediated autophagy underlie α-synuclein aggregation and neurodegeneration

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

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7 January 2021

Interplay of LRRK2 with chaperone-mediated autophagy

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7 January 2021

Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy

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https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

The Effect of Parkinson's-Disease-Associated Mutations on the Deubiquitinating Enzyme UCH-L1

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7 January 2021

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

1 reference

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7 January 2021

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43.

1 reference

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7 January 2021

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

The role of chaperone-mediated autophagy in huntingtin degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model

1 reference

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7 January 2021

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy markers in Parkinson disease brains

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Genetic analysis of the LAMP-2 gene promoter in patients with sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Regulation of amyloid precursor protein processing by its KFERQ motif

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

1 reference

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7 January 2021

LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Acetylation targets HSD17B4 for degradation via the CMA pathway in response to estrone.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Lamp2a is required for tumor growth and promotes tumor recurrence of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

CMA down-regulates p53 expression through degradation of HMGB1 protein to inhibit irradiation-triggered apoptosis in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

M2 tumor-associated macrophages produce interleukin-17 to suppress oxaliplatin-induced apoptosis in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Role of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cells

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7 January 2021

Chaperone-mediated autophagy degrades mutant p53.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Activation of chaperone-mediated autophagy as a potential anticancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Methods to monitor chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Degradation of AF1Q by chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Targeted suppression of chaperone-mediated autophagy by miR-320a promotes α-synuclein aggregation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Altered expression of autophagic genes in the peripheral leukocytes of patients with sporadic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Reduced expression of the chaperone-mediated autophagy carrier hsc70 protein in lymphomonocytes of patients with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated Autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Inhibition of PI3K/AKt/mTOR signaling pathway protects against d-galactosamine/lipopolysaccharide-induced acute liver failure by chaperone-mediated autophagy in rats.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

The Detrimental Role Played by Lipocalin-2 in Alcoholic Fatty Liver in Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

The Impact of Autophagy on the Cigarette Smoke Extract-Induced Apoptosis of Bronchial Epithelial Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Suppression of chaperone-mediated autophagy in the renal cortex during acute diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy components are upregulated in sporadic inclusion-body myositis muscle fibres

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-Mediated Autophagy after Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Chaperone-mediated autophagy is defective in mucolipidosis type IV.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0001-6

7 January 2021

Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein

1 reference

12 December 2020

Altered degradation of proteins microinjected into senescent human fibroblasts

1 reference

12 December 2020

Selective binding and uptake of ribonuclease A and glyceraldehyde-3-phosphate dehydrogenase by isolated rat liver lysosomes

1 reference

12 December 2020

Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state

1 reference

12 December 2020

Unique properties of lamp2a compared to other lamp2 isoforms

1 reference

12 December 2020

A molecular chaperone complex at the lysosomal membrane is required for protein translocation

1 reference

12 December 2020

Abnormal chaperone-mediated autophagy (CMA) in cardiomyocytes of a boy with Danon disease

1 reference

12 December 2020

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

1 reference

12 December 2020

HDAC6 Regulates the Chaperone-Mediated Autophagy to Prevent Oxidative Damage in Injured Neurons after Experimental Spinal Cord Injury

1 reference

12 December 2020

10.1038/S41580-018-0001-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6399518&resulttype=core&format=json

13 May 2020

PubMed publication ID

29626215

1 reference