(Q52584637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

title

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

Prostaglandin-endoperoxide synthase 2

23 March 2020

main subject

1 reference

GOA release 2020-03-11

Sphingosine kinase 1

1 reference

GOA release 2020-03-11

author

Seung Hyun Kim

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

11

Edward H Schuchman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Ju Youn Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Seung Hoon Han

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Min Hee Park

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Bosung Baek

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Im-Sook Song

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Min-Koo Choi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Yoh Takuwa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Hoon Ryu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Xingxuan He

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Jae-Sung Bae

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Hee Kyung Jin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

language of work or name

English

0 references

publication date

16 April 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

1479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

23 March 2020

copyright license

start time

16 April 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5902554/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-018-03674-2

0 references

cites work

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A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

3 July 2018

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Neuropeptide Y regulates the hematopoietic stem cell microenvironment and prevents nerve injury in the bone marrow

3 July 2018

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Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology

3 July 2018

1 reference

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Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

3 July 2018

1 reference

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Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease

3 July 2018

1 reference

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Pro-resolving lipid mediators are leads for resolution physiology

3 July 2018

1 reference

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Proresolving lipid mediators and mechanisms in the resolution of acute inflammation

3 July 2018

1 reference

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Resolution of inflammation is altered in Alzheimer's disease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

The microtubule-associated tau protein has intrinsic acetyltransferase activity

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation

3 July 2018

1 reference

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The immunology of stroke: from mechanisms to translation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Expression of sphingosine kinase 1 in amoeboid microglial cells in the corpus callosum of postnatal rats.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Aspirin in Alzheimer's disease: increased risk of intracerebral hemorrhage: cause for concern?

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

3 July 2018

1 reference

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Neuronal 'On' and 'Off' signals control microglia

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Essential role for sphingosine kinases in neural and vascular development

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics

3 July 2018

1 reference

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Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

3 July 2018

1 reference

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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Relative contribution of acetylated cyclooxygenase (COX)‐2 and 5‐lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

3 July 2018

1 reference

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Subregion- and cell type-restricted gene knockout in mouse brain

3 July 2018

1 reference

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Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Anti-inflammatory drugs and Alzheimer disease.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Substrate binding to chloramphenicol acetyltransferase: evidence for negative cooperativity from equilibrium and kinetic constants for binary and ternary complexes.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Microglia emerge as central players in brain disease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Non-selective NSAIDs improve the amyloid-β-mediated suppression of memory and synaptic plasticity.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid β ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Bone marrow-derived mesenchymal stem cells attenuate amyloid β-induced memory impairment and apoptosis by inhibiting neuronal cell death

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Dissection, plating, and maintenance of cortical astrocyte cultures.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Isolation and culture of adult neurons and neurospheres

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902554

Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells

13 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-03674-2

7 January 2021

inferred from DOI database lookup

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-03674-2

7 January 2021

inferred from DOI database lookup

The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-03674-2

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/S41467-018-03674-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29662056%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

PubMed publication ID

29662056

1 reference