(Q52590998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Somatic mutations of ErbB4: selective loss-of-function phenotype affecting signal transduction pathways in cancer (English)

1 reference

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18 January 2020

1 reference

7

1 reference

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18 January 2020

Maija Hollmén

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

5

Susanna Repo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Denis Tvorogov

1

1 reference

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18 January 2020

Maria Sundvall

2

1 reference

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18 January 2020

Kari Kurppa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Mark S Johnson

6

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

19 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

18 January 2020

published in

1 reference

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18 January 2020

volume

284

1 reference

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18 January 2020

issue

9

1 reference

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18 January 2020

page(s)

5582-5591

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

Cell signaling by receptor tyrosine kinases

18 January 2020

cites work

1 reference

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ERBB receptors and cancer: the complexity of targeted inhibitors

21 January 2018

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An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

21 January 2018

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Mechanism of activation and inhibition of the HER4/ErbB4 kinase

21 January 2018

1 reference

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The conformational plasticity of protein kinases

21 January 2018

1 reference

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c-erbB-4/HER4: friend or foe?

21 January 2018

1 reference

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Role of ErbB4 in breast cancer

21 January 2018

1 reference

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Somatic mutations of the ERBB4 kinase domain in human cancers

21 January 2018

1 reference

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

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Colorectal cancer: mutations in a signalling pathway

21 January 2018

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21 January 2018

The Protein Data Bank

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BODIL: a molecular modeling environment for structure-function analysis and drug design.

21 January 2018

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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

21 January 2018

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

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GROMACS: fast, flexible, and free

21 January 2018

1 reference

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Development and validation of a genetic algorithm for flexible docking

21 January 2018

1 reference

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Comparison of the biochemical and kinetic properties of the type 1 receptor tyrosine kinase intracellular domains. Demonstration of differential sensitivity to kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells.

21 January 2018

1 reference

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

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Active and inactive protein kinases: structural basis for regulation

21 January 2018

1 reference

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Impact of EGFR point mutations on the sensitivity to gefitinib: insights from comparative structural analyses and molecular dynamics simulations.

21 January 2018

1 reference

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ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

The deaf and the dumb: the biology of ErbB-2 and ErbB-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

A census of human cancer genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

21 January 2018

1 reference

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Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

An investigation of the role of Glu-842, Glu-844 and His-846 in the function of the cytoplasmic domain of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Survival of cancer cells is maintained by EGFR independent of its kinase activity

21 January 2018

1 reference

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The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805438200

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

21 January 2018

1 reference

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Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M805438200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19098003%20AND%20SRC:MED&resulttype=core&format=json

release_t6fwcpxemnap3lkpw7c3gm6ajq

18 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/t6fwcpxemnap3lkpw7c3gm6ajq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference