(Q52596786)

4 May 2018

title

Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. (English)

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4 May 2018

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5

Mary L Bouxsein

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4 May 2018

Stacy H Shomento

1

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4 May 2018

Chao Wan

2

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4 May 2018

Xuemei Cao

3

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4 May 2018

Marie-Claude Faugere

4

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4 May 2018

Thomas L Clemens

6

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Ryan C Riddle

7

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4 May 2018

publication date

1 January 2010

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4 May 2018

Journal of Cellular Biochemistry

published in

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4 May 2018

volume

109

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4 May 2018

issue

1

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4 May 2018

page(s)

196-204

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4 May 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

cites work

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Quantitative microcomputed tomography analysis of collateral vessel development after ischemic injury

21 January 2018

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

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Remodeling and vascular spaces in bone

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

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Acute postnatal ablation of Hif-2alpha results in anemia

21 January 2018

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Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells

21 January 2018

1 reference

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

21 January 2018

1 reference

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

21 January 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

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Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway

21 January 2018

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Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo

21 January 2018

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Developmental regulation of the growth plate

21 January 2018

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Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

21 January 2018

1 reference

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

21 January 2018

1 reference

Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells

21 January 2018

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Damaging fatigue loading stimulates increases in periosteal vascularity at sites of bone formation in the rat ulna

21 January 2018

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HIF-1alpha and HIF-2alpha play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle

21 January 2018

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

21 January 2018

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Molecular mechanisms of endochondral bone development.

21 January 2018

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

Signal transduction to hypoxia-inducible factor 1

21 January 2018

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HIF-1 mediates the Warburg effect in clear cell renal carcinoma

21 January 2018

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

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The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.

21 January 2018

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Increase of both angiogenesis and bone mass in response to exercise depends on VEGF

21 January 2018

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Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCB.22396

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4 May 2018

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4 May 2018