(Q52731934)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Metabolic features of cancer stem cells: the emerging role of lipid metabolism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

main subject

neoplastic stem cells

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Gennaro Ciliberto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

author name string

Rita Mancini

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Alessia Noto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Maria Elena Pisanu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Marcello Maugeri-Saccà

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

language of work or name

English

0 references

publication date

15 February 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

page(s)

2367-2378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41388-018-0141-3

17 March 2020

exact match

0 references

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Presurgical window of opportunity trial design as a platform for testing anticancer drugs: Pros, cons and a focus on breast cancer

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7 January 2021

Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer

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7 January 2021

Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

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7 January 2021

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial.

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7 January 2021

Evidence for biological effects of metformin in operable breast cancer: biomarker analysis in a pre-operative window of opportunity randomized trial

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Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial.

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7 January 2021

Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial.

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7 January 2021

Presurgical trial of metformin in overweight and obese patients with newly diagnosed breast cancer

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7 January 2021

Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study.

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7 January 2021

The effect of metformin on apoptosis in a breast cancer presurgical trial.

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7 January 2021

Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study

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7 January 2021

Immunological hallmarks of stromal cells in the tumour microenvironment

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7 January 2021

Inhibitory effect of tumor cell-derived lactic acid on human T cells

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7 January 2021

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.

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7 January 2021

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

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7 January 2021

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

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7 January 2021

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

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7 January 2021

Acidic pH enhances the invasive behavior of human melanoma cells

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7 January 2021

Acid-mediated tumor proteolysis: contribution of cysteine cathepsins

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7 January 2021

Cancer cell metabolism: one hallmark, many faces.

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7 January 2021

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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7 January 2021

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

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7 January 2021

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.

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7 January 2021

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

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7 January 2021

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling

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7 January 2021

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

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7 January 2021

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

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7 January 2021

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

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7 January 2021

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

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7 January 2021

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

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7 January 2021

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

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7 January 2021

Clonal evolution in cancer

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7 January 2021

Heterogeneity in cancer: cancer stem cells versus clonal evolution

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7 January 2021

Cancer stem cell metabolism

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7 January 2021

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

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7 January 2021

Acidic stress promotes a glioma stem cell phenotype.

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7 January 2021

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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7 January 2021

Prospective identification of tumorigenic breast cancer cells

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7 January 2021

Identification and expansion of human colon-cancer-initiating cells

1 reference

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7 January 2021

Identification and expansion of the tumorigenic lung cancer stem cell population

1 reference

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7 January 2021

Identification of human brain tumour initiating cells

1 reference

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7 January 2021

Identification of pancreatic cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Tumorigenic and metastatic activity of human thyroid cancer stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Complexity of cancer stem cells

1 reference

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7 January 2021

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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7 January 2021

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

1 reference

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7 January 2021

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Efficient tumour formation by single human melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Therapy-induced enrichment of putative lung cancer stem-like cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Genetic variegation of clonal architecture and propagating cells in leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Metabolic plasticity in stem cell homeostasis and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Critical appraisal of the side population assay in stem cell and cancer stem cell research

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Energy metabolism characterization of a novel cancer stem cell-like line 3AB-OS.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The secretome of colon cancer stem cells contains drug-metabolizing enzymes

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Interplay between metabolic identities in the intestinal crypt supports stem cell function

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Lipid metabolic reprogramming in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Lipid rafts as major platforms for signaling regulation in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Targeting metastasis-initiating cells through the fatty acid receptor CD36

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Detection of lipid-rich prostate circulating tumour cells with coherent anti-Stokes Raman scattering microscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

EMT markers in lung adenocarcinoma pleural effusion spheroid cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The biology of YAP/TAZ: hippo signaling and beyond

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

The interplay between cell signalling and the mevalonate pathway in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Mevalonate metabolism regulates Basal breast cancer stem cells and is a potential therapeutic target.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Metabolic control of YAP and TAZ by the mevalonate pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Targeting protein prenylation for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0141-3

7 January 2021

Amino acid, glucose, and lactic acid utilization in vivo by rat tumors

1 reference

12 December 2020

Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts

1 reference

12 December 2020

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release

1 reference

12 December 2020

Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells.

1 reference

12 December 2020

10.1038/S41388-018-0141-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29445137%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference